Does Ibuprofen Help With The Discomfort Of Gastritis?

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Gastritis is an inflammation, irritation, or erosion of the stomach lining, which can come on suddenly and last a short time (acute) or start gradually and be long-lasting (chronic). It is caused by stomach acid irritates the inflamed tissue of the stomach. Treatment usually involves taking drugs to reduce stomach acid, which can help relieve the pain.

NSAIDs, such as Advil (ibuprofen), aspirin, or Aleve (naproxen), can irritate the digestive tract, leading to irritation of the stomach lining. Overuse of NSAIDs, such as aspirin and ibuprofen, is one of the most common causes of acute gastritis. Some patients may need to stop taking these pain relievers and talk to their healthcare professional about stopping anti-inflammatory painkillers or aspirin and trying a different medicine, if possible.

The treatment of gastritis depends on the specific cause. Acute gastritis caused by NSAIDs or alcohol may be relieved by stopping use of those substances. The most common symptoms of gastritis are stomach upset and pain. Long-term use of NSAIDs, such as ibuprofen (Advil, Motrin) or naproxen (Aleve), may be recommended by healthcare professionals.

In summary, the healing period for gastritis depends on the cause and the duration of treatment. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as Advil, Aspirin, and Aleve, can cause both acute and chronic gastritis. It is important to consult with a healthcare professional before taking these medications, as they can interfere with the production of mucus.

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Gastritis: What It Is, Symptoms, Causes & TreatmentThe overuse of nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin and ibuprofen, represents one of the most prevalent causes of acute gastritis. It should be noted that some…my.clevelandclinic.org
Gastritis – Symptoms and causesNonsteroidal anti-inflammatory drugs (NSAIDs), a category of pain relievers, have been linked to the development of both acute and chronic gastritis. Nonsteroidal anti-inflammatory drugs (NSAIDs) have been linked to the development of both acute and chronic gastritis.www.mayoclinic.org
Gastritis: MedlinePlus Medical EncyclopediaIt may be necessary to discontinue the use of aspirin, ibuprofen, naproxen, or other medications that may be contributing to the development of gastritis. It is imperative to consult with a healthcare professional in all cases.medlineplus.gov

📹 What Ibuprofen Does to the Body

____ What Ibuprofen Does to the Body ____ In this video, Jonathan from the Institute of Human Anatomy discusses how ibuprofen …


Can I take ibuprofen if I have gastritis?

You may need to stop taking aspirin, ibuprofen, naproxen, or other medicines that may be causing gastritis. Always talk to your health care provider before stopping any medicine.

You may use other over-the-counter and prescription drugs that decrease the amount of acid in the stomach, such as:

  • Antacids
  • H2 antagonists: famotidine (Pepcid), cimetidine (Tagamet), and nizatidine (Axid)
  • Proton pump inhibitors (PPIs): omeprazole (Prilosec), esomeprazole (Nexium), Iansoprazole (Prevacid), rabeprazole (AcipHex), and pantoprazole (Protonix)

Antibiotics may be used to treat gastritis caused by infection with Helicobacter pylori bacteria.

The outlook depends on the cause, but is often very good.

What is the best pain relief for gastritis?
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What is the best pain relief for gastritis?

Acid blockers, also called histamine blockers, reduce the amount of acid released into your digestive tract. Reducing acid relieves gastritis pain and encourages healing. You may get a prescription for an acid blocker, or you can buy one without a prescription.

Diagnosis. Your healthcare professional is likely to suspect gastritis after talking to you about your medical history and performing an exam. However, you also may have one or more of the following tests to find the exact cause.

Tests for H. pylori. Your healthcare professional may recommend tests such as a stool test or breath test to determine whether you have H. pylori. Which type of test you have depends on your situation.

For the breath test, you drink a small glass of clear, tasteless liquid that contains radioactive carbon. H. pylori germs break down the test liquid in your stomach. Later, you blow into a bag, which is then sealed. If you’re infected with H. pylori, your breath sample will contain the radioactive carbon.

Does ibuprofen help with gastric pain?
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Does ibuprofen help with gastric pain?

Avoid nonsteroidal anti-inflammatory drugs—ibuprofen (Advil, Motrin) and naproxen (Aleve)—when you have a stomachache. These drugs are hard on the stomach and can make a stomachache worse.

When to see a doctor. If your stomachache or surrounding pain is severe, lasts more than two days, or if you have additional symptoms such as fever, weight loss, vomiting, or diarrhea, call your doctor.

Many patients Krishnareddy sees expect the worst. But fewer than 2% of stomachaches are life-threatening or surgical emergencies. “We can always find the bad stuff,” says Krishnareddy, highlighting gallstones and pancreatic cancer, conditions that occur in less than 15% of the population. Most stomachaches, about 70%, are not severe.

Can I take ibuprofen for gastroenteritis pain?

Because gastroenteritis is caused by viruses, antibiotics are not used. If you have a fever, headache or muscle aches, you can use acetaminophen (Tylenol). Avoid ibuprofen or aspirin on an empty stomach. Try the following to advance diet: • If vomiting, rest your stomach by not eating until 24 hours without vomiting.

What makes gastritis pain better?
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What makes gastritis pain better?

In most cases, you will be given antacids and other medicines to reduce your stomach acid. This will help ease your symptoms and heal your stomach lining.

If your gastritis is caused by an illness or infection, your healthcare provider will also treat that health problem.

If your gastritis is caused by the H. pylori bacteria, you will be given medicines to help kill the bacteria. In most cases, you will take more than 1 antibiotic and a proton pump inhibitor. A PPI is medicine that reduces the amount of acid in your stomach. Some cases are complicated and need multiple medicines. It’s important to take them as prescribed. Contact your healthcare provider if you have side effects or are confused about how to take them.

Can gastric patients take ibuprofen?
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Can gastric patients take ibuprofen?

After surgery, you should avoid nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, ibuprofen (Motrin, Advil) and naproxen (Aleve). NSAIDs increase the risk of stomach ulcers. Patients who had gastric bypass surgery should avoid these medications indefinitely. If you had a sleeve gastrectomy procedure, you might be able to resume taking these medications after the sleeve heals (about three months after surgery), but consult your bariatric surgery team first.

Vitamin and mineral supplements. To prevent nutrient deficiencies, bariatric surgery patients need to take the following vitamin and mineral supplements daily:

  • Multivitamins. After surgery, taking a daily bariatric-specific multivitamin helps compensate for nutritional deficits. Bariatric-specific multivitamins include high doses of all necessary micronutrients, simplifying your postsurgical supplement regimen. The ProCare Health bariatric multivitamin can be purchased online without a prescription.
  • Calcium. We recommend taking 1, 000 to 1, 500 milligrams of calcium daily to prevent calcium deficiency and bone loss. Calcium citrate is the preferred form. To enhance absorption, reach the daily total by taking two or three divided doses over the course of the day. For example, take a 500-mg chewable or capsule supplement two or three times a day.
  • Vitamin D3. This is in both the multivitamin and calcium supplement we recommend after surgery. The ProCare Health bariatric multivitamin has 3, 000 international units (IU) of vitamin D3, and the Celebrate calcium supplement includes 500 IU per chew or capsule. You are therefore getting about 4, 000 IU of vitamin D3 daily.
How can I get immediate relief from gastritis?
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How can I get immediate relief from gastritis?

Here are some options to help relieve your gastritis pain as quickly as possible:Take over-the-counter antacids. Take medication that lowers stomach acid. Avoid alcohol consumption. Eat ginger or foods with ginger in them. Garlic has also been shown to relieve gastritis. Drink light beverages like chamomile tea.

One of the most uncomfortable health problems to have is gastritis. Gastritis is defined as inflammation of the stomach lining, most often caused by certain bacteria, though other factors can also cause it. If left untreated, gastritis can become quite painful and cause a range of different symptoms.

In fact, the longer you go without treating gastritis, the harder it is to relieve the many different symptoms it causes and get back to your day. So, knowing how to relieve gastritis pain fast is very handy.

What Causes Gastritis. Before we talk about how to relieve gastritis pain fast at home and different forms of gastritis treatment, we should mention the causes of gastritis so that you can hopefully avoid them and decrease the number of episodes you may experience.

What is the fastest way to cure gastritis?
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What is the fastest way to cure gastritis?

For fast gastritis relief, a person will probably need to use over-the-counter medications that block or reduce stomach acid. Examples include calcium carbonate (Tums) or omeprazole (Prilosec). Learn more about antacids.

Mild gastritis typically resolves independently, and eating specific foods will not heal it. However, eating and drinking the following may reduce the risk of developing gastritis in the first place:

  • Green tea
  • high fiber foods
  • low acidity foods and drinks
  • low fat foods
Which painkiller is best for gastric pain?
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Which painkiller is best for gastric pain?

The best medicine for stomach pain includes:Aluminum hydroxide. … Milk of magnesia. … Simethicone. … Omeprazole. … Cimetidine. … Domperidone. … Sucralfate. … Clarithromycin.

Medicine for stomach pain like sodium bicarbonate, omeprazole or cimetidine can help to reduce pain and burning, as they act by inhibiting the stomach acid production, or neutralizing the acidity in the stomach. Some may also increase how quickly the stomach empties its content.

Stomach pain is usually caused by excess acid production, excess gas, gastritis, stomach ulcers, gastroesophageal reflux or eating contaminated food. In addition to stomach pain, these conditions can cause vomiting and diarrhea. Read more about what can cause stomach pain.

How long will gastritis pain last?
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How long will gastritis pain last?

Gastritis may last for only a short time (acute gastritis) or it may linger for months to years (chronic gastritis).

The esophagus, stomach, large and small intestine, aided by the liver, gallbladder and pancreas convert the nutritive components of food into energy and break down the non-nutritive components into waste to be excreted.

The stomach connects the esophagus to the small intestines and is where the majority of food digestion takes place.

How can I calm my gastric pain?
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How can I calm my gastric pain?

Drink plenty of clear fluids such as water. Reduce your intake of coffee, tea and alcohol as these can make the pain worse. When you are allowed to eat again, start with clear liquids, then progress to bland foods such as crackers, rice, bananas or toast. Your doctor may advise you to avoid certain foods.

  • Abdominal pain is pain felt anywhere from below your ribs to your pelvis.
  • Abdominal pain usually goes away without surgery and most people only need relief from their symptoms.
  • If pain persists or if you have any other concerns, see your doctor.

This page has been produced in consultation with and approved by:

This page has been produced in consultation with and approved by:


📹 IBUPROFEN AND ULCERS

Every day, millions of people take meds known as NSAIDs to relieve their pain. But, many aren’t aware that these popular drugs …


Does Ibuprofen Help With The Discomfort Of Gastritis?
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Elle Pierson

Hi, I’m Elle Pierson, RN, MBA—a passionate Healthcare Consultant dedicated to empowering individuals and organizations to achieve better health outcomes. As a TEDx Speaker, Author, and Mentor, I bring my expertise in medicine and healthcare management to help others navigate complex systems with confidence. My mission is to inspire change and create meaningful solutions in the world of healthcare. Thank you for joining me on this journey!

Education: Bachelor of Science in Nursing (BSN) and Executive MBA from Texas Woman’s University.
Email: [email protected]

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89 comments

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  • I took ibuprofen every day for over a year. Ended up throwing up blood one night with no idea why, went to the ER and got diagnosed anemic, as well as the cause of the bleeding of course linked to way too much ibuprofen. could have died in my sleep at any moment honestly. The affects of this really should be talked about more if you take it in large amounts!

  • my wife almost died several years ago from taking Ibuprofen everyday with Coca Cola in the morning. It actually ate a whole in her stomach and she almost poisoned her own body. The surgeon had to cut out the bottom of her stomach and reattach the intestine. Then it had a small leak and she almost poisoned herself again due to that leak. My wife is now in her last semester of nursing school and will be a nurse in December. We love these articles. I am the husband Greg typing on my wife’s account. hahahaha

  • TLDW: Generally safe for the liver, it can thin out the protective barrier in the stomach but is pretty safe if taken here and there, kidneys are also fine but it causes vasoconstriction which can worsen existing kidney issues if taken daily for other issues. In summary, try not to take it daily or too frequently and you’ll likely be fine. I’m not a doctor just summarizing his content.

  • I’m a doctor from France and I must say THANK YOU for your great educational articles where I often learn new things, rediscover some others and where I am always amazed by the beauty of human anatomy. Thank you for your pedagogy and your dedicated work 🙏🏼 your are a treasure of knowledge and spreading of this knowledge. And, off course a BIG THANK YOU for the people who donated their body for this marvelous science your are producing 🙏🏼🙏🏼🙏🏼

  • I took Ibuprofen regularly throughout high school and college almost every day. I have sever migraines from my seizure disorder so I was actually given Ibuprofen for that reason. But one night I was sleeping, and as I snored, I could feel something coming up the back of my throat. Turns out it was blood and I was bleeding internally. I was rushed to the ER and the doctors told me I had severe damage to my esophagus and early liver damage, similar to that of an alcoholic. I obviously don’t take it anymore but I watch how much I eat and stay from foods or substances that make my liver and esophagus flare up.

  • 9:10. 9:40. 13:20. 14:29. Some people need to be educated on just dismissing taking ibuprofen on a daily basis. People have told me that their family member or friend is a PA and that taking all this ibuprofen is not going to hurt someone. Thank goodness I educate myself and try to stay away from medication due to its potential side effects. More people need to read up on this before spewing misinformation. Thank you, sir, for your valuable article.

  • For those of us who live with chronic pain, we really don’t have much choice in the matter. I have 3 herniated disks in my lower back (for the last 36 years) as well as a seriously degenerated left hip (for the last 10 years). I’ve had one hip surgery, which did not alleviate my chronic hip pain, and have used high doses of ibuprofen to manage my pain for DECADES. Seems those of us who manage chronic pain using ibuprofen are damned if we do (do to side effects) and damned if we don’t (living with high levels of persistent pain). We need better solutions to chronic pain that what is currently available…

  • I’m 68. I never heard anyone explain something as clear, easy to understand, and thorough as this. Excellent sir!! Thank you! I occasionslly take a 500mg tablet of Naproxin. But I was always afraid to take one because I drink 2- five drinks a day. When I do take one,I have something to eat first, and drink a glass of milk. I don’t know if that helps my liver,or kidneys, or stomach, but I don’t feel any side effects, but I will say the 500mg Naproxin works 100% to eliminate any pain. Like when I lifted something too heavy,and had low back pain.💊pain💨

  • My brother who was an Ophthalmologist himself, past of lung cancer a few years ago. He donated his body to science. I hope that his contribution has benefited those who are learning the science of medicine. He was an awesome teacher, friend and brother. Much missed. Blessings to those who have gone before us.

  • In 1977 (while in the military) I was prescribed Motrin (Ibuprofen) for “stress headaches.” Migraines were a reason for discharge, so the doctor was doing me a favor because I was close to retirement. Long story short. I continued to use Ibuprofen, sometimes like candy, for the headaches, knee pain and muscle pain until about 2013 when I was diagnosed with kidney cancer. I had part of my right kidney removed and have been cancer free, I hope. In 2018 I broke my neck and still suffer from nerve pain daily. I still take Ibuprofen on rare occasions because it helps. My doctor checks me for any hint of cancer every six months. Bottom line, Ibuprofen works great for the pain but I limit how often I take it. Otherwise, I grin and bear the pain as long as I can.

  • This article is a very good reminder that biology is a complex thing, based on endless interactions between entities. No matter how hard we try to create products that benefit us, there will always be a point where it can become dangerous, because it’s all a matter of equilibrium to make everything work smoothly, and these products offset that balance just as much as the afflictions we can encounter. Always be careful with your body, that’s how it’ll last to the fullest of its abilities.

  • My doctor prescribed 3200 mg ibuprofen daily for inflammation. I told her I was not comfortable doing that because the dosage was too high. She convinced me to do it because she said there was no other treatment option besides surgery. So I took it, and after a week, I started having bad stomach pain. My doctor was out of the office when the symptoms started, so I went to a different doctor who told me that I should stop taking the medication immediately because I was bleeding internally.

  • Thank you for this article. I have kidney disease and stopped taking Ibuprofen and other NSAIDs immediately when I found that out. I never knew WHAT NSAIDs did to the kidneys, and your explanation put it all into place for me. I like to be informed and I am thankful for this website! You have helped me a great deal!

  • I’ve been taking ibuprofen for 20+ years for arthritis and scoliosis pain. When pain was at its worse, I was taking 6 to 8 a day. After a SI joint fusion my pain level has decreased significantly and now take 2 – 4 per day. I never take it on an empty stomach, I always drink plenty of water and my doctor monitors my kidney and liver functions through yearly wellness exams. So far, so good. I have also learned that ibuprofen increases your blood pressure so be aware of that during your doctor visits.

  • A side effect you didn’t mention is intestinal bleeding. I took advil periodically for joint inflammation. Never made the connection between the bleeding and advil use until I was taken down with Guillian-Barre syndrome. The bleeding caused an infection in my colon that produced proteins that closely mimicked the proteins found in the myelin sheathing around the nerves. It wasn’t the typical case of GBS. it put me in the hospital for 10 weeks and left me with permanent damage to both my peripheral and autonomic nervous systems. I can tell you it’s no fun not being able to feel the ground below my feet while walking.

  • I remember one time I was 12, had to go to a hospital because of severe dehydration, stomach pains and rashes all over my body. I was having an allergic reaction due to an undiscovered histamine intolerance and was also severely allergic to ibuprofen. We wouldn’t find out about that until I was being pumped full of ibuprofen by nurses and having an extreme allergic reaction on top of my already ongoing histamine allergic reaction. I still remember how weak I felt, that burning tingling sensation all over my body and not being able to eat or drink anything properly for three days. I got better, but had to keep coming back again and again, year after year with the same issues until we finally found a doctor who could diagnose my intolerance and allergies. I’m insanely thankful for the efforts of the doctors and nurses to keep me safe and heal me. But I really wish this type of stuff would be researched more carefully by hospitals and medical schools in order to avoid putting anyone else through so much pointless pain, so much time and resources spent and wasted, when it could all be avoided

  • Not sure how this article ended up making its way to my suggested articles but I’m glad it did. I’ve always heard the side effects but never the “why.” Today I got my answer. Glad I only take the stuff as needed, low and slow. One 200mg pill to start, and another 45-90mins later if I still have pain. Generally speaking I try to stay away from any form of medicine unless absolutely necessary.

  • Thank you for this particular article because it hits home for me. I have ESRD, on my 2nd renal transplant, and now I understand why my nephrologist told me that Ibuprofen is bad for renal patients. I love the clear explanation of every step of the process. It blows mind that science can be able to explain all this. Thanks to all who are involved in research, including the donors who donate their bodies to science.

  • Thank you for this informative and helpful learning article. You must know by now your teaching style is highly effective. The “show and tell” aspect helps drive home the points you are trying to make. It’s quite enlightening how you help us visualize the body’s reaction to NSAID’s on a multi-organ standpoint. Your voice and bearing induce an almost hypnotic effect on the learners and make us want to stick around to see just where you are going. Kudos, sir! I only subscribe to the best and you are worthy. Lol.

  • I highly appreciate the time & effort you put into making a rather complicated topic more understandable to a lay person like myself. Thanks also to those who donated their bodies to science so other can learn. I will also be a donor one day. Your enthusiasm about your profession and teaching make it all the more interesting. A heartfelt thank you.

  • Fantastic article! I seriously flashbacked to med school. The dangers of NSAIDs are both grossly overstated and understated. Larger doses taken continuously over a long period of time can have serious side effects such as bleeding stomach ulcers or kidney damage. On the other hand, they’re not strychnine. Taking them here and there will treat many problems effectively with minimal risk.

  • This has to be the best presentation format for medical study anywhere on the internet. I feel like what you describe in this way is more retainable than with 2D (or even 3D) graphics. Its a mixture of your bringing out process details and showing the physical layout simultaneously. I don’t know if this is true for others, but for me it works great!

  • I’m so glad you are sharing this. I was taking Tylenol, ibuprofen and Aleve for sciatic pain. I started taking 1 Tylenol every other day, and sometimes times I’d switch and take ibuprofen. I increased to taking ibuprofen 1 every day. Within 6 months lab reports showed my liver enzymes increased from 22 to 153. I’m 75 and don’t take any other medication. I stopped taking all ANSIDS. Thank God all other vitals are good.

  • I really wish I had discovered your articles when I was taking anatomy and physiology in college! I love the way you explain things thoroughly in your articles that makes way more sense than my professor at the time! And to the deceased who donated their bodies to science in order to better understand the human body, thank you. ♥️🙂

  • This is really interesting! About a year ago I was diagnosed with an acute kidney injury that has since repaired itself. The doctor told me it was because I was taking ibuprofen most days for nearly a decade because of chronic migraines, as well as taking it without food as well as being extremely dehydrated. They said I can’t have ibuprofen anymore. It’s really interesting to know more about how this happens!

  • It also can cause Tinnitus .. and auditory damage. ❤ you and your energy so much and great smile!! I cant listen any due to my disability reactive tinnitus, hyperacusis and noxacusis but still see your light shining. ❤️🧡💛 please raise awareness for prople to protrect their auditory sytem from damage. It can steal silence and the ringing and sound sensitivity have no limit to how bad they can torture you. Ive been homebound with all sounds causing pain and increased ringing since april 2022. These afflictions are so gaslighted and i dont want another beautiful soul to fall into them. Sorry for the spam. Please warn everyone you can to protect their auditory system in all ways. All meds, vaccines can cause ringing and neurological problems. I love you all. Keep sharing your light!!

  • I never gave much thought to NSAIDs when I was a kid, I had bruises and breaks and would need them for maybe three weeks. I learned a lot about arthritis meds when my wife was diagnosed with rheumatoid arthritis. The Dr explained how a whole science of drugs came into being to be able to allow patients to use pain killers for there entire life without damaging the liver, kidney or stomach, and switching them so as not to allow the body to become used to them.

  • After seeing some of the comments section, let me say this: it’s okay to take medication, just be responsible with it. For example, I have hypothyroidism. Without levothyroxine, I would be in a much worse place. I would be tired all the time, bloated, and other symptoms associated with the condition. I wouldn’t be able to live life as fully as I do right now. I believe that medications are invented for a reason and that taking them responsibly can improve health.

  • I have to agree with so many of the other people’s comments. The way he teaches this information is fantastic. You’re in the right profession, sir. I look forward to more educational articles from you in the future. Shout out to the individuals who donated their bodies to science. Without them, those in the medical field wouldn’t have this amazing resource to practically learn the human body. Thank you!

  • I believe it’s half of the reason why my body broke down ten years ago along with chronic stress. I used to eat the stuff along with Excedrin and sometimes Aleve but that didn’t work well on my pain so I mostly took Advil and Excedrin. For many years and rarely two. Always needed three, sometimes four. I had bad back pain and hip pain. I got horrible neck aches and headaches and migraines. So at 47 or so I had heartburn and found out I had Barrett’s Disease. Other than the incessant over the counter drug usage I took okay care of myself. I drank wine from time to time and coffee in the mornings and maybe periodically in the afternoon but that’s it. Then my body had a total breakdown at 48/49yrs old and I went thru early menopause and was done with it by 50/51yrs old. I have had a lot of gastro problems too and I attribute most of it to excessive Ibuprofen and aspirin usage as well as chronic stress. I’m now 60 and still fighting chronic severe pain daily as well as being sick. I tell my kids and everyone if they take OTC medicine for pain to make sure at least to do so with food and/or milk to help coat the stomach lining. That’s nothing scientific but I took it without food many many times. When you’re young it doesn’t bother you but after years of it, it will. I’ve lost the last ten years of my life to sickness and pain. I can’t get them back. I never feel good enough to do anything extra other than what I HAVE to do at home daily (chores). Never get to spend time with my grandkids or visiting loved ones.

  • I really enjoy perusal your articles. If I have a question I watch your articles and usually get the answers. Right now, i’m currently on 800 mg of Ibuprofen. I am supposed to take 3 times a day, but I only take it one time a day. I asked my doctor the other day if it did anything to me, and he said no, not really. I now know more by listening to your articles.Thank you so much for all your information.

  • Where was this guy when I was doing Biology in school he explained the kidneys in 3 minutes where it took my teachers 3 months and he did it so straight forward. I ended up dropping the subject because the teacher left a lot to self study and I struggle with understanding certain subjects if not explained. In short thank you very much.

  • Love this article. I’m so glad I stopped taking it.I was taking it to do my sport but I had a bunion. I heard it broke down articular cartilage and so I stopped. That was counterintuitive. I ended up getting surgery and never had pain again. Never take this regularly. Don’t mask pain. There’s a reason!! Thank you for this article!!!

  • The article I didn’t know I needed, thank you!! I used to work as a pharmacy assistant and have always known the side effects but never knew exactly how ibuprofen was the catalyst. Can you please also do similar articles on other common NSAIDS (diclofenac, paracetamol, naproxen, aspirin, etc)? This is so fascinating!

  • Interesting. So it’s not the pill itself that directly damages the stomach. But rather the indirect systemic effects of Ibuprofen on the stomachs ability to produce mucus, and in turn protect itself, from itself. I’ve always been under the impression (having been told by others), that I must take Ibuprofen with food, otherwise it will damage my stomach. So that’s not strictly true then. It’s more about the long-term effects that Ibuprofen can have on the stomach.

  • I had a friend who in his words, was popping them like candy for a back problem. Eventually, he perforated his large intestine. Needless to say, it was a big problem. He had 3 surgeries and they removed a significant portion of his intestine. He was permanently disabled after this incident. I’m always mindful of his experience when I take Ibuprofen for my back pain.

  • Ibuprofen almost killed me. My organs shut down and had I not been found, Drs said by morning I would have either been in coma or dead. My kidney is pretty much healed after 7 years. Now I cannot use any NSAID. Be careful and don’t take too much! If you are in pain, call your Dr, and don’t worry about bothering someone if you need something at the pharmacy.

  • Where was this guy when I was in nursing school? He is wonderful!! I used to buy 2 or 3 books on the same subject so I would get the full picture. during my time text books were $65.00 to $100.00 a pop. It was helpful getting different authors opinions on topics. But this guy is great. I would have loved to have been able see Institute of Human Anatomy

  • I was suffering from significant sciatic pain from 2009 to 2014. I was taking 4 Ibuprofen two or three times a day while also sometimes drinking several shots worth of rum in the evenings. I cut back to 3 Ibuprofen 3 times a day as recommended by my doctor. In 2014 a pain doctor figured out my femoral neck was causing the pain. Cortisone in just the right spot has cured me. I now take 2 or 3 ibuprofen a couple times a year.

  • I stopped taking ibuprofen several years ago when I developed an allergic reaction. I had taken the same amount as I always had, because I was having a headache. About an hour later, my lips started to swell up really bad. I went to the doctor and received an allergy shot. I haven’t taken ibuprofen since.

  • Really enjoyed this article! I wish it went more into the consequences of taking too much ibuprofen too often. I’m an ICU nurse and lately I’ve taken care of a couple of patients whose doctors prescribed them ibuprofen for their pain, which they took daily. They got ulcers in their GI tracts and had life threatening bleeds and were completely unaware that ibuprofen could cause it.

  • I’ve watched several of these articles as they relate to the kidneys since I have had kidney stones. I now better understand why the doctors tell you what to do and not do like drink a lot of water and do not take ibuprofen. Most of all I appreciate those who donated their bodies to make these articles possible. Looking at the real thing is a lot different than looking at illustrations and plastic models. You have a better appreciation for what is actually part of your body.

  • Hey Doc, Awesome physiology lesson! I needed Ibuprofen on a trip to Europe and was amazed at the caution they had prescribing it about 5 years ago. I don’t take it unless I absolutely have to now, mostly due to that experience. This explains why. Love love love the kidney breakdown! Keep up the good work.

  • This is a gret article! Almost lost my grandma for a stomach ulcer outburst after she took prescribed Ibuprofen for a couple days (there were probably other contributing factors too, but the ibuprofen was the matchstick). Gladly she recovered (slowly) after receiving blood transfusion and being hospitalized. Take care of your body guys, black poop may be a be a bad sign sometimes.

  • My sister-in-law used to take naproxen sodium (Aleve, another NSAID) every single day for months in order to control joint and muscle pain in her ankles. She said it was the only thing that gave her consistent relief. The price she paid for that was a peptic ulcer that almost killed her — burned a hole in her stomach and acid leaked out and started irritating everything in the vicinity of the stomach. Required emergency surgery to save her. If there’s anything to avoid it’s a steady diet of NSAIDs. If the pain is that chronic or severe then it’s not something to try to self-treat with OTC meds, otherwise the cure might ultimately be worse than the disease.

  • I’ve been taking Ibuprofen since I was 8 against heavy migrane attacks and they’ve been my saviour for almost 20 years now. No side effects no nothing. Without it I wouldn’t have been able to sleep and probably cried for several hours (which isn’t exactly smart when you already have a migrane/headache). It was also really useful after an acid accident to numb the pain along with some other pain killers that were prescribed with the Ibuprofen. What I want to say is.. it can do good..it can probably do bad as well if taken too much or often .. you just gotta make sure you take it when you REALLY need it.

  • I had severe tooth pain and couldn’t afford to go to a dentist. Tylenol alone didn’t kill the pain so I added ibuprofen to help. Over 2 years I took it every six to 8 hours — 3 or 4 tablets at a time. My eGFR was very low. Doc asked me if I’d done anything to bring it on and I couldn’t think of anything until I looked up the side effects of Advil. Here I am, a pharmacist who’d totally forgotten this crucial side effect. Today I am ok but it took 6 months to get the numbers of my GFR within a normal range. Dialysis would not have been fun

  • I took 4 ibuprofen every 4 hours around the clock for about 3 months when I had MRSA, and had no side affects that I know of. That was about 8 years ago. This article was actually very reassuring, and extremely informative! I don’t recommend my dosage, but I think the possible damage has been hyped unnecessarily by others. This was a balanced presentation; very helpful.

  • I sure do have something to say about this…. 20 years ago, I stopped taking this because I became a health freak and would take no pills for anything. I had learned about them and didn’t want them in my body. I suffered with about 3 migraines a year and I took nothing for them. I had the worst case of strep throat and took nothing. I came home from a vacation in Mexico and was so sick and I took nothing. Last week, I got hit with a brutal headache and I went and picked up some advil migraine and it was such great relief that I denied myself for 20 years. Now, it’s everything in moderation for me. I will take it about 3 times a year and I’m perfectly okay with that. Sometimes I suffered needlessly. Still, don’t regret being pill free for 20 years. I’m sure it did wonders.

  • Being a very senior senior citizen, I no longer take ibuprofen due to the irritation of the stomach. I read where a doctor stated that we would be better off taking narcotics than ibuprofen, even with the risk of dependency. The doctor mentioned that seniors rarely go bad and start holding up liquor stores to pay for drugs.

  • I’ve had chronic back pains for decades, Doctors prescribe ibuprofen but I refuse to take it apart from when it gets really bad. I actually decided to look at my diet and started cutting out coffee, bread, pasta and reducing the sugary foods and especially the processed foods, replaced it with salads and fruit and veg and those pains reduced dramatically within days. Our society is set up to make us ill and then make us pay to get treated with medicines that don’t really work.

  • Great article! To share some first-hand data I would like to talk about my situation, I have been taking 2 pills of ibuprofen 400mg daily for around 3 years now. This is for my knee pain, so far so good, no kidney problems at all yet I drink a lot of water 2 liters minimum per day. I know that is not the best strategy but it helps me to walk without pain.

  • When I was a young woman, I suffered from stage four endometriosis. My gyn prescribed 800 mg of Ibuprofen 3 times per day. It was the only med that was even mildly effective for my pain. Years later when hospitalized for another reason, I learned I had kidney damage and an insufficiency. Now i cannot take any nsaids, have to be very careful with diuretics, be careful to always hydrate with water, and have frequent blood work to check my kidney function. I will always live with this reminder that meds are not always good for you. Be informed.

  • Some people with asthma (like myself) can actually be highly allergic to ibuprofen. I learned the hard way after taking only half a dose and then having labored breathing, diarrhea, and stomach pain for hours. I almost had to go to the ER. This happened twice before I realized it was the ibuprofen. In my case, it turned out that I have a rare condition called Samter’s Triad. Having an allergy to ibuprofen is a apparently a telltale sign, along with a few other factors.

  • My brother was recently hospitalized with ulcerative colitis, and the doctors said it could’ve been caused/triggered by consuming ibuprofen. He had been taking a lot of ibuprofen (5-6+ tablets), often daily/every other day, usually before a workout (usually weightlifting). It’s been a couple of years and he still has frequent flare-ups and is on medication to control his UC, and likely will for the rest of his life.

  • Ibuprofen is an amazingly cost effective short-term drug. here in the UK it costs $0.43 for 16 x 200mg caplets. Unfortunately people can all-to-often lean on it for chronic pain and given it is a non-prescription medication sold in the same aisle as toothpaste and deodorant people can assume it’s harmless. Thanks for highlighting the specific areas that people should be aware of

  • These articles are excellent! Do you think you could do one about conditions like Ehlers Danlos Syndrome, Marfan’s and other connective tissue disorders? I understand you may have to limit what you talk about (because those conditions can affect A LOT of different body processes), but it would be great to see more awareness around these disorders. I’m in one of the most populous cities in the US and I’m having trouble finding a rheumatologist that actually knows about EDS!

  • I was prescribed 8 to 10 ibuprofens a day when I was in the 9th grade for jr rheumatoid arthritis. I was told they could affect my hearing?? I came to faith in Jesus. I asked a couple in my church if Jesus would heal me. They said yes if you’re willing to forgive anyone who you’re holding something against. I said I would. They lead me in prayer and I forgave my father who had been abusive and they prayed for me and I just believed Jesus was going to heal me. I stopped taking meds, my swollen sore joints went back to normal. I’m a grandmother now. No arthritis. Still love Jesus ❤

  • I’ve done my research and learnt about effects of ibuprofen so I have years I don’t take it and due to my gastritis but somehow I’ve had doctors prescribed me ibuprofen for reason and I mention to them my stomach isssues and they just tell me it’s fine 🤦🏻‍♀️ but still don’t take it. Many in the comments here seems they just take ibuprofen without reading the labels or paying attention to other issues with their body. Let’s do some research first. This article is awesome! 👏🏻

  • I didn’t realize how large some of the organs are. Very neat and interesting article, thank you! I was eating ibuprofen twice a day, 1600 mg total a day for joint pain from an auto immune disease. It eventually caught up with my stomach and I started having issues. I tried some natural remedies, turmeric-worked a little bit, but nothing like the ibuprofen. I think I finally found something that works and haven’t had to use ibuprofen in weeks now and not in crippling pain when I wake up. Collagen I, II, III, V, X types. Knock on wood, hope it keeps working.

  • Four months ago I took a pill of ibuprofen on an empty stomach because a headache was keeping me from sleeping. Not a chronic user, hadn’t taken one in years. I woke up with excruciating pain an hour later. After that day, my stomach was destroyed. Couldn’t eat anything besides yogurt without throwing up for a week. My stomach and intestines were in pain constantly. Formed new food sensitivities and an egg allergy overnight. My stools were neon green to yellow for three months…. Very very slowly coming out of it …. Never take ibuprofen on an empty stomach

  • Very good presentation however I would add the followings: The common NSAID’s also cause the body to retain more Sodium ( Na) and less of its filtration/ elimination through the kidneys hence increasing the blood pressure (a known side effect) . They also tend to increase the heart rates hence together with an increased blood pressure they increase the risks of heart attacks and strokes . People with hypertension ( high blood pressure) and/or those with other cardiovascular diseases must avoid taking it

  • Great article. I suffered from nephritis and kidney failure after taking Ibuprofen for 7 days (600mg/1:1:1) last November. No kidney problems before that, pretty sporty & healthy in general. So be careful even with common /”every day” drugs. Certainly the reaction of my body was exceptionally heavy, but I always thought of Ibuprofen as something completely harmless before. Cheers and stay healthy 😎

  • I pretty much quite all pain medications years ago. I want the pain, so that I stop doing what hurts me. The body does provide pain management though. When I am athletically involved, my endorphins kick in, and I’m able to perform. So long as I keep going. Once stopped thought, getting started again can be really hard to do, depending on how physically stressed I happen to be. One thing though that does interest me, is recovery. I like things that help right-size inflammation. Fighting insulin tolerance is helpful here, and I do periodic fasting—and feel great from it. Thank you for the information. This helps me understand what is essentially a practical, but overlooked, understanding of what I happen to be, as a thing. David

  • I took ibuprofen in the 80s while in the USAF. Never told to take with food and every 8 hours at 20 years old. Are my stomach lining and was on the hospital a week while my stomach lining recovered. I’ll suffer with the current pain. Now I have cysts on kidneys, kidneys stones and peeing is not good. Doctors STILL try to give me it. Thanks. Great information. Not saying ibuprofen have me stones but probably didn’t help.

  • Thank you! Thank you for making it so simple, clear to understand, and keep me interested THROUGHOUT the whole article. You touched not only on the medical parts but on the practicality of making the right choices (amount of ibuprofen needed, own judgment, whether we are hydrated, etc.) and implicitly maybe, what we just ate if we want to care about the stomach lining protection and last but not least why it would be bad or an important consideration for people with liver or kidney disease. Thank you! I just subscribed too. Clear information, and of course, if something seems wrong, consult with the doctor, but being well informed helps on the doctor consultation next time it’s needed.

  • I’ve read a study and observed myself that taking half the recommended dose of BOTH acetaminophen (paracetamol) and ibuprofen works as good as if not very very slightly better than taking the full dose of either alone. I believe they don’t interact but I’m not certain. I know that you should NEVER take ibuprofen and aspirin at the same time, as it can cause internal bleeding to my knowledge due to aspirin being a blood thinner and ibuprofen being a similar drug. Also to my knowledge ibuprofen is more effective than aspirin for pain relief.

  • High doses of nonsteroidal anti-inflammatory drugs (NSAIDs), longer duration of use, or greater frequency of use are all associated with an increased risk for Crohn’s disease and ulcerative colitis, according to findings of a study presented here at the American College of Gastroenterology (ACG) 2011 Annual Scientific Meeting.

  • My Dad’s kidney doctor told him ibuprofen brought more patients in for kidney failure than alcohol or any other drug/reason. I am also drug tested once a month, and sometimes if I take ibuprofen close to the time of the test, I run the risk of a false positive for Adderall, lol. It’s happened to me before. I had no clue that could happen. Nowadays I rarely take it. Only when absolutely necessary. I used to take it every day like an aspirin just to get through the workday. I did that for years admittedly. That was a horrible habit to have, and also a hard one to break away from. Seeing what my father goes through now helps keep me away from it, though. I REALLY don’t want to end up going in for Dialysis three times a week (5-8 hours a day), taking countless meds just to survive, go on a renal diet (or die), etc.

  • I found this article very interesting! I have taken Ibuprofen for years as part of treatment for arthritis, thankfully not as often anymore as we found long term options that work really well. However earlier this year I had to take strong doses of ibuprofen for hip issues and it caused my stomach real issues. I had to go to the ER because of the sudden intense pain. Since then, I am thankfully doing much better. Really enjoyed learning more about the process from an organ perspective!

  • My doctor told me to take Ibuprofen to manage pain issues I had from tendinitis in both arms from my jobs. Never mentioned any side effects. I used it everyday for several years. Don’t remember how much. However I noticed I had to pee more and more often producing less & less urine. My own research revealed the possible problem to be the Ibuprofen. I had to retire early due to the tendinitis, Never having been told that Ibuprofin could be causing my kidney problem. It took years of NOT using it to no longer have the effects. 😢

  • My golden rule is “try to avoid painkillers (or pills in general) as MUCH as you can”, I personally had a tooth problem, that appeared once in 4-6 months (2-3 times a year), and I was taking painkillers whenever that problem occurs, but after 2-3 years, I realized its much better to simply go and fix the damn tooth, even tho it troubled me like 2-4 times a year for few days only, than to overload stomach with painkillers every half a year… (turned out it was wisdom teeth failing to grow up cause of lack of space, so I had a surgery to remove it, no need for meds anymore, in a long time). Bottom line, better to get to the “root” of problem, and fix it, than mend the pain with pills over and over again.

  • I love the website! Showing different processes using actual human organs helps a ton in understanding concepts that might seem simple on the surface … but are definitely complex. Plus a smart, communicative, hot doctor doesn’t hurt either … for the learning experience I mean 😊 (sorry if it’s a weird comment 😅)

  • Took ibuprofen and other over the counter painkillers when I first developed CRPS. I took really large amounts on a schedule that my PCP gave me. Promptly went onto kidney and liver failure after a couple months. Meanwhile, I’ve been on opioid painkillers for about a decade after that happened. No abnormal kidney or liver numbers. And I can walk again. Just proves that any medication can be dangerous, but dangerous medication can be helpful if you take it right.

  • This is a great article. It reminded me of when i took 800mg of ibuprofen every six hours when i first had two herniated discs in my spine. My doctor said it was okay, and it was the only thing that reduced the pain, but i was still concerned about it. I also took 800mg of ibuprofen when i had covid recently. It was the only thing that helped my body feel better from the awful body aches i had. Outside of those situations, i try not to take much medicine too often.

  • This article was absolutely amazing. I subscribed right away. I have been battling kidney stones since I was 7. Ibuprofen was what I always took for the pain. Just 2 weeks ago, I had to have two stones removed from the left urethra because they were 2.5 cm in size and they were blocking the urine causing my left kidney to swell. The doctor put stents in each of my kidneys. Those things hurt like hell, epecially when coupled with little shards of stones that remained after the stones were bursted with laser. I was super tempted to go back to Ibuprofen, because I don’t like the feeling I get from the prescribed hydrocodone. The doctor told me not to take ibuprofen. Now I know why. Thanks so much for making this article. I guess thanks to youtube algorithm for suggesting this article.

  • Absolutely brilliant (no pun intended!) article, everything that you said just slotted logically into place. I wish I had followed this path more… probably would of if there had been an internet when i was a student. I remember being part of an autopsy and you learn so much more when you are dealing with the real thing rather than pictures and drawings. 👍

  • Thank you for the information. I knew ibuprofen had interactions with the kidneys, but I had bad reactions with tylenol that affects the liver. Every individual reacts differently to all medication. I have had a few surgeries and given several different pain meds (Vicodin, Tramadol and Oxycodone). I found that all those medications have a base pain relief ingredient, but are mixed with different ‘fillers’. I had a difficult time with Vicodin and Tramadol was better for my pain relief. Know Oxycodone has been in the media for years, but it was the best pain relief for me. Ask your doctor to change your medication if it does not work for you.

  • With every NSAID my body has become horribly allergic to them. I get swollen stomach and intestinal tracks creating unbelievable pain that at one point drs removed my appendix thinking it was the problem. It wasnt. I have arthritis so tylenol is my only option for pain relief. Nobody writes opioids anymore, so yes I live with non stop pain.

  • 9:20 This is what happened to me. The Army had me on Ibuprofen (800mg) and Tramadol (50mg) for pain management for almost 10years. Combine that with the excess of alcohol I was drinking to help combat the pain and I’ve really done a number on my stomach. They told me I have Gastritis with Metaplasia, which I was told meant I was one step from stomach cancer. I got this diagnosis 5 years ago, and I’m still trying to fix my stomach. Like a comment below, I woke up one morning and vomited a large amount of bright red blood. I felt like I was dying at the time.

  • Well this was nice to watch. I took multiple painkillers on a daily basis for years now, mostly Ibuprofen although sometimes I change it to something different so that my body won’t get used to Ibuprofen too much and it stops working as intended. Strange thing though is that one of my doctors said that taking Ibuprofen this long daily will mess up my blood which I found kinda strange, but now I kinda have a slight idea what she was talking about.

  • I was prescribed max dose ibuprofen for 8 months at which point blood tests showed I had elevated liver enzymes. Scans showed I had morphological liver changes and fatty liver – these stayed for 10 years until I did keto/IF which gave my liver enough of a break to allow itself to heal (although that itself took a further 2 years and is ongoing).

  • Question for people in the comments who’ve had bad side affects from taking ibuprofen: some are saying how often they took it, but not how much. In my experience, you can only find 200 and 400 mg tablets in shops, but there might be higher doses available via prescription or in other countries. In my house we always take ibuprofen after eating something to lessen the impact, and keep paracetamol on hand if the pain isn’t super bad/we want a bit of a top-up a couple hours after taking ibuprofen, but I just wanna know to be safe

  • Have to also think of intestinal ulcers too, as that warning came on boxes of Rx Vioxx. When I had a compression fracture on top of a herniated disc at L5, I was bed ridden for at least the first week and then mostly until it was able to heal (couldn’t have surgery, another story). To deal with having to shop for groceries back then (no delivery back then), I’d take 1 Aleve the day before, 1 Aleve the day of getting out (plus a back brace), & 1 Aleve the day after to deal with the intense pain I was in. I found out then that 3 days in a row was the most I can take Aleve because I would then having burning & acidic intestinal cramps & a block of burning diarrhea that I could feel make it’s way through my intestinal track! Thank goodness I eventually healed enough I could stop that, but that was definitely not a fun time in my life! And I’m fortunate to not have had any lasting damage (that I know of) from doing that once weekly just to be able to get groceries!

  • I was ordered double dose of this from a doctor when i was younger. Had much pain in the back, it was not straight I was told later from a chiropractor. Anyway this doctor did just a quick look and gave me this double dose. 5 to 6 days later my lower stomach, intestine i guess had a super big bump. About 40 mm high and 50 mm long. I immediately stop taking the drug and the bump vanished after some days. Then did go to a chiropractor instead to fix back…

  • 3:27 if it’s an immediate release tablet (the typical kind), by the time the stomach is emptied (let say 30 minutes) the pill/tablet/caplet/lozenge/capsule/pastille would have dissolved almost completely depending on the dissolution profile of the tablet (typically 30 to 45 minutes). Modified/prolonged/delayed release, or gastric coated medicine do not start the dissolution process until reaching the intestines where the pH allows the formulated product to dissolve.

  • I find these fascinating. I would love a article/s on type 2 diabetes along with how different food groups are processed by the body. My dad is really struggling to get his head round managing his type 2 diabetes. He doesn’t get why just cutting out sugar doesn’t work because he is still eating loads of carbs or 2-3 pieces of fruit at a time.

  • I took Ibuprofen when I was 11 and got Stevens-Johnson Syndrome. Went in to get checked-out when I wasn’t feeling well, told them all I took was Ibuprofen, the doctors basically shrugged and prescribed me more. Woke up the next morning choking on the skin inside of my mouth which had peeled away and turned into stringy spaghetti-like strands of flesh, the rest of my skin was becoming spotty and getting ready to fall off as well, my face swelled like a balloon, it hurt to use the bathroom in any way, I couldn’t taste anything, I had to eat only liquid foods and was given other pain relief to allow me to, otherwise they were going to tube me, my lungs have been seriously permanently damaged, my eyesight got worse, my nose constantly dries out and bleeds, I have regular heartburn now. I was in the hospital for weeks and my family was getting ready to move before I got sick and I never got around to telling my friends we were moving, to them I just disappeared one day after complaining about not feeling well, and I completely lost contact with them. Yet somehow still, as far as I know, no one is forced to warn about Stevens-Johnson Syndrome despite it being a confirmed side-effect and destroying mine and others lives, and the supreme court has thrown out lawsuits against these companies for failing to warn about it. I used to love running, one of my most treasured childhood memories includes me outrunning all my friends including older ones, while running backwards. I loved biking, tubing, and hiking with my family.

  • Thank God for Ibuprofen🙏 Since my doctor has prescribed me 600mg tablets, it’s been a lifesaver. As a 65 year old man that has moderate arthritis, over the past 10 years my quality of life has improved dramatically. The main thing is to only take the minimum you need..and to have your labs performed every 3 months.

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