Quality enzyme products use the standard FCC (Food Chemical Codex) units of measurement to establish activity levels for their enzymes. However, there are other units used in biomedicine, such as Alpha-Galactosidase (GALU) and Amylase (DU), which are used to measure enzyme activities.
To ensure high-quality digestive enzymes, it is essential to learn how to read a digestive enzyme label and compare products. Enzyme units, enzyme activity, and specific enzyme activity are often confused, but this guide explains these concepts in simple terms and discusses enzyme assay design and the FIP unit.
One unit of enzyme activity (FIP Unit) is defined as the quantity of a standard lipase preparation that liberates the equivalent of 1 micromole of fatty. In biomedicine, the FIP unit corresponds to the quantity of enzymes. Enzymes are biological catalysts that increase the rate or speed of a chemical reaction without being used up in the process.
Protease (HUT), amylase (DU), lipase (FIP, LU, FCCLU), and cellulase (CU) are all important units of activity. The International Pharmaceutical Federation (FIP) is another measurement used for enzyme activity in supplements, while FIP stands for Fédération Internationale Pharmaceutique (USP).
Feline infectious peritonitis (FIP) is a complex disease of cats that occurs worldwide and is most prevalent among cats under 3 years of age. Enzymes are biological catalysts that enhance the speed of a chemical reaction without being used up in the process.
| Article | Description | Site |
|---|---|---|
| Amazon.com: Customer Questions & Answers | FIP represents a unit of measurement for digestive enzymes. The measurement of enzyme potency in dietary supplements is a more complex process than that of measuring vitamin potency. | www.amazon.com |
| Papain (Papaya) | This is expressed in either F.I.P. units or U.S.P. units. F.I.P. is an acronym for the French term “Fédération Internationale Pharmaceutique,” while U.S.P. stands for “United States Pharmacopeia.” These units are expressed in the following manner: | www.mikronaehrstoffcoach.com |
📹 FIP in Cats: The Complete Guide (and new treatment option)
FIP in cats – three initials that strike fear into every cat owner who knows how deadly this disease can be. While the virus that …
What is a FIP unit of enzymes?
The effectiveness of enzymes to enable to conversion of substances is described as enzyme activity. It is a measure of the catalytic activity of enzymes and mirrors the substrate turnover per unit of time. The parameter for enzyme activity is the katal (kat), whereby 1 kat corresponds to a turnover of 1 mol, that is 6 x 10 23 substrate molecules per second (mol x s -1 ). A commonly used measurement used in medical literature is the International Unit (U), whereby one U corresponds to the turnover of 1 µmol of substrate per minute (µmol x min s -1 or 16. 7 x 10-9 kat). Another measurement used for enzyme activity in biomedicine is the FIP unit (Fédération International Pharmaceutique), whereby 1 FIP unit corresponds to the quantity of enzymes which convert 1 µmol of a defined substrate in 1 minute under standard conditions.
Enzymes have highly specific functions by only converting specific substrates (known as substrate specificity) and exhibit a distinct specificity of effect, i. e. only enabling a certain substance conversion. So that they can unfurl their full activity, many of them are reliant on “activators”. These additionally required components are referred to as cofactors. These firstly involve minerals such as magnesium, iron and copper, as is the case for metalloenzymes or metal activated enzymes. Other enzymes, in contrast, require organic or metal-organic cofactors, which are referred to as coenzymes. Many vitamins are components of coenzymes.
Multi-enzyme complexes can improve the digestive capacity of people with a reduced digestive capacity and also those with a fully functioning digestion to achieve a higher absorption of nutrients.
What is the abbreviation for enzyme unit?
The enzyme unit, or international unit for enzyme (symbol U, sometimes also IU ) is a unit of enzyme ‘s catalytic activity.
1 U (μmol/min) is defined as the amount of the enzyme that catalyzes the conversion of one micro mole of substrate per minute under the specified conditions of the assay method.
The specified conditions will usually be the optimum conditions, including but not limited to temperature, pH, and substrate concentration, that yield the maximal substrate conversion rate for that particular enzyme. In some assay method, one usually takes a temperature of 25°C.
The enzyme unit was adopted by the International Union of Biochemistry in 1964. Since the minute is not an SI base unit of time, the enzyme unit is discouraged in favor of the katal, the unit recommended by the General Conference on Weights and Measures in 1978 and officially adopted in 1999.
What are the two units of enzymes?
Some common units used to express enzyme activity include:International Units (IU)Katal (kat)Units per milligram (U/mg)Units per liter (U/L)
How do you convert FIP to USP?
Actual enzymatic activity. Baseline lipase, amylase, and free and total protease activity levels were determined for each sample in accordance with procedures specified by the Fédération Internationale Pharmaceutique (FIP) and the European Pharmacopoeia (PhEur). Results were converted from FIP/PhEur units to USP units as follows: for lipase, 1 FIP/PhEur unit = 1 USP unit; for amylase, 1 FIP/PhEur unit = 4. 15 USP units; and for protease, 1 FIP/PhEur unit = 62. 5 USP units. 33 Actual enzymatic activity was compared as a percentage of label claims. All assays of baseline enzymatic activity were performed at least in duplicate.
Resistance of enteric coating to simulated gastric acid. Product samples were agitated in a disintegration apparatus in a solution of 0. 1 N hydrochloric acid (pH 1) at 37°C for 120 minutes to simulate gastric conditions. Then the undissolved portion of the samples was separated from the solution, and the residual lipase activity was determined and reported as percentage of the actual lipase activity determined in the first part of the study and as percentage of label claim. All tests of the resistance of the enteric coating to simulated gastric acid were performed at least in triplicate.
Kinetics of simulated duodenal lipase release. New product samples were agitated in a disintegration apparatus designed to simulate intestinal peristalsis for 60 minutes at 37°C at pH 5. 0. Then the pH was adjusted to 6. 0, and the test was continued for an additional 60 minutes. Samples were withdrawn every 15 minutes for determination of the activity of the lipase that had been released from the enteric coating. The results at each time point were reported as percentage of the actual lipase activity determined in the first part of the study and as percentage of label claim. All tests of lipase release kinetics were performed at least in triplicate.
What does FCC stand for?
The Federal Communications Commission The Federal Communications Commission regulates interstate and international communications by radio, television, wire, satellite, and cable in all 50 states, the District of Columbia and U. S. territories.
Are alu and FCC the same?
The label states that 20 alu or acid lactase units, while a generic lactase has 9, 000 FCC lactase units. To convert between these standards, one can look at lactase tablets, which are 9000 units. The Revly digestive enzymes have a limited amount of lactase, so it is not a substitute for the other.
Tolerase L, a product with a dosage of 2, 500 ALU per 10-13 grams of lactose consumed, is recommended for lactose-intolerant consumers. The European Food Safety Authority recommends a dose of 4, 500 ALU with each lactose-containing meal. For very sensitive lactose-intolerant consumers (requiring a 100 conversion), 10, 000 ALU per meal is recommended. Over time, consumers will quickly establish their required dose.
FCCs and ALUs of lactase are the same unit of measurement, and they may be written as ALU, FCC, or FCC ALU. The label also mentions that a generic lactase has 9, 000 FCC lactase units, but the user cannot find a conversion chart.
In conclusion, both FCCs and ALUs of lactase are the same unit of measurement, and one should stick with their current lactase enzymes. The dosage of Tolerase L depends on the amount of lactose and the size of the meal consumed, with a general guideline of 2, 500 ALU per 10-13 grams of lactose consumed.
What does FIP pipe stand for?
FIP stands for female iron pipe. This type of fitting is characterized by inside threading and is sometimes referred to as FPT (female pipe thread) because it can be made from materials other than iron.
Threads are the ridges found in or outside a pipe fitting that allow you to attach them to another pipe. Threads have peaks and valleys called crests and roots and an area in between the two called a flank. You can always find the threading on FIPs inside the fitting.
MIP vs. FIP. FIPs are designed to attach to pipe and hose fittings with outside threading, like MIPs (male iron pipes). Like FIPs, MIPs are sometimes called MPTs (male pipe thread) because they’re not made exclusively from iron. MIPs are designed to be placed into FIPs. Many licensed plumbers will also secure the MIP threads with plumber’s tape before inserting into a FIP to fill in the gaps between crests and roots and prevent leaks.
These kinds of pipe fittings are commonly used to connect gas lines to appliances like dryers, heaters, and washing machines. For this reason, using the appropriate-size FIP or MIP is essential to preventing potential hazards like gas leaks.
What is FCC in enzyme?
Enzymes are quantified based on their activity. Unlike some other active ingredients, measuring based upon mass is not appropriate, as that would not outline the potency of the enzyme. Different enzymes use different units to quantify their activity. The Food Chemical Codex (FCC), outlines internationally recognised units of measure for enzymes, alongside the testing methodologies.
See below a range of enzymes we have available alongside their activity. Please note, that we also have a range of diluted enzymes to facilitate with dosing.
DU- One α-amylase dextrinizing unit is defined as the quantity of α-amylase that will dextrinize soluble starch in the presence of an excess of β-amylase at the rate of 1 g/h at 30°C. The degree of hydrolysis is determined by comparing the iodine colour of the hydrolysate with that of the standard. (FCCVIII)
What does FIP stand for?
Feline infectious peritonitis (FIP) is a viral disease in cats caused by certain strains of the feline coronavirus, known as feline enteric coronavirus (FeCV). Infected cats usually do not show symptoms during the initial infection but may experience brief bouts of diarrhea and mild upper respiratory signs. They mount an immune response, producing antibodies against the virus within 7-10 days. In about 10% of cats infected with FeCV, one or more mutations can alter its biological behavior, resulting in white blood cells becoming infected with the virus and spreading it throughout the cat’s body. This interaction between the body’s own immune system and the virus is responsible for the development of FIP.
FIP typically occurs in two forms: a “wet form” where fluid accumulates in body cavities like the abdomen and/or chest, and a “dry form” that affects the central nervous system, causing neurologic signs. Once a cat develops clinical FIP, the disease is usually progressive and almost always fatal without therapy. The availability of safe and effective therapies for FIP represents a dramatic advancement in veterinary medicine, and it is recommended to consult with a veterinary professional team if you have questions about acquiring FIP therapy for a cat suffering from this disease.
Yearly cats are at greater risk of developing FIP, with approximately 70 of cases diagnosed in cats less than 1 1/2 years of age and 50 in cats less than 7 months of age. The most common mode of transmission of FeCV is believed to occur when infected queens pass the virus to their kittens, usually between five and eight weeks of age. Cats housed in high-density facilities, pure-bred cats, male cats, and geriatric cats are also more susceptible to FIP development.
What does FIP stand for in mechanical terms?
FIP, or Female Iron Pipe, thread is a type of threaded connection used primarily in plumbing and hydraulic systems. It is characterized by its tapered threads designed to create a tight seal when engaged with a corresponding Male Iron Pipe (MIP) thread. The taper of FIP threads helps to ensure a secure fit and seal as the threads are tightened, making it suitable for applications where leak prevention is critical.
The development of FIP thread standards can be traced back to the early advancements in plumbing and fluid handling industries. Over time, standards such as those set by ANSI/ASME have standardized the dimensions, pitch, and taper angles of FIP threads, ensuring uniformity and compatibility across different manufacturers and applications.
The evolution of FIP thread standards reflects ongoing efforts to improve thread performance and reliability in diverse environments. These standards have been pivotal in enabling the widespread adoption of FIP threads across various industries, providing engineers and technicians with confidence in their application and longevity.
What is the terminology enzyme?
An enzyme is a biological catalyst and is almost always a protein. It speeds up the rate of a specific chemical reaction in the cell. The enzyme is not destroyed during the reaction and is used over and over. A cell contains thousands of different types of enzyme molecules, each specific to a particular chemical reaction.
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An enzyme is a biological catalyst that is usually a protein but could be RNA. The point of a catalyst is to increase the speed with which a reaction happens. And there are many, many enzymes that are encoded by the genome to make proteins or RNAs that speed up various chemical reactions to do thousands of different functions inside a cell.
📹 The BATTLE for my cat’s life against Feline Infectious Peritonitis FIP
This is Keith’s story. Timestamps 0:00 0:34 overview 0:51 the adoption 2:19 the signs 3:32 the investigations 5:11 the difficulty in …
Thank you for helping to spread the word that FIP is no longer a death sentence. My cat was diagnosed with wet FIP back in May, and the vet told us he only had days or weeks to live. Luckily, I found FIP Warriors and was able to get a vial of GS locally. I injected him for 84 days straight and then another 84 days of observation. Today he is cured and happy and healthy. I’ve since treated 4 foster kittens with FIP, one is in observation and doing amazing.
Until very recently, I’d never even heard of FIP. I lost my 8 month-old kitten to it a couple weeks ago and I still cry for him. We were very closely bonded and when I had to put him to sleep I felt like I was killing a part of myself along with him. The disease just overwhelmed him entirely. His symptoms started on a Tuesday and he was dead the following Tuesday. That’s how fast he deteriorated. The vet only diagnosed FIP on his last day. Up until then, he was hospitalised on a drip and I was getting daily updates saying he seemed to be doing well. That he’s “bright and alert”. Turns out he only appeared that way because he was over-stimulated and had a seizure on his last day. He was jaundiced, thin as a rake and couldn’t breathe without assistance. I broke down into an inconsolable wreck when I saw him to say goodbye. My poor boy. He tried to get up when he saw me but collapsed. I asked if he was in pain and the vet said he’s definitely uncomfortable. So the decision was made. He died with his head resting in my hand and I buried him at my nan’s house with the other cats that came before him. He was the sweetest little thing. Even when I had him neutered, the vets told me they fell in love with him. That he’s a real cuddler. He’d run down the stairs to greet me after work, taught himself to play fetch, and LOVED cuddles and kisses. He broke the typical stereotypes of cat behaviour. His name was Cupid, because of how loving he was. Never will there be another like him in my life.
Hi, Im sad, depressed and anxious atm, just woke up after crying myself to sleep last night. I have a male kitten/cat (he’s around 5 months old) his name is Oreo. When we first bought that beautiful boy back in september, he was such a playful, happy kitten. Hes a persian cat with the lightest most pulchritudinous soft fur. I used to sleep with him and then got replaced with my brother who later became his best friend. My mother liked cats but her only problem was poop training. Thankfully Oreo’s pooped trained already, so no more concerns. My mom wasnt a fan of cats ever but when we bought oreo ..he became my moms most fav child. He unfortunately got infected with fungal infection, his fur on his ears started falling off, we rushed to the doc and he gave us some medicines, a diet plan and a shampoo with which we were supposed to give him a bath everyday. My mom did all the struggle despite 1000 other things to do. Fortunately, everything got back to normal after a month of struggle by both us and oreo. Just right after 2 weeks Oreo started to look lethargic and pretty indolent. He’d sleep most of the time, wont eat food either, there was a white lining on the corners of his eyes. We took him to the vet where he told us that oreo had fever we were scared to death but he told us to come the next 3 days consistently for injections(4-6 injections per day) God knows how much pain he would’ve went through..AGHHH..so when that medication was complete, Oreo started feeling better, he’d spend time with us, eat food properly, he’d eat so much he started having a big belly and we used to make fun of him saying how this lil boy is eating too much now he is a fat catto, he started to seem a lil weak again and we took him to the vet again, where LITTLE DID WE KNOW .
Our cat developed FIP last year (he was 2 years old at the time) and we got the GS treatment and after a little less than a 100 days he was cured. It’s been now just a year after the end of the observation period and our cat is doing amazing! Absolutely no side effects in our case and he’s recovered really nicely and is a whole new cat with a lot of energy. Healthy as an ox.
I had to put my baby down yesterday due to FIP. It was 5 days after his 1st birthday. I woke up and found him lying flat on his side. He could not move his body on his own, I could see that he was barely breathing. I grabbed him and ran to the vet as soon as I could. He had symptoms of both wet and dry FIP. He was so far gone I knew it would be selfish and cause him more suffering if I didn’t just have him put to sleep. He was the sweetest cat I’ve ever had and my life isn’t the same without him. Rest In Peace Ozzy 🐈⬛😢❤️
My cat had the typical fluid on the abdomen but also could not eat or drink water, he acted like he had hydrophobia, scared to death of water, tried to put water in his mouth and he would choke and resist, worthless vets could tell me nothing, but took lots of my money I just gave up and had him put down, at the time of death a strange fluid drained out of his nose, they couldn’t tell me what that might be either, maybe somebody out there might have seen that before. The experience left me with a disdain for vets, no one seemed to care about me or the cat, they were eager for me to sign for expensive worthless testing and treatment.
my cat is 8 years old and was diagnosed with wet FIP. i’ve read that there’s loads of success stories with GS… but it’s unapproved in australia. the fine can be between $1,998 and $166,500 AUD, as well as civil or criminal penalties if imported. their reasoning was that unregistered products to treat pets is harmful. lol my cat is dying? what more of a risk can GS pose to my dying cat? i’m so angry.
Took in a polydactyl TNR from my colony who vanished for 2yrs and returned with lice, fleas,a tick and very sickly with an URI…he lived for 3mos inside…warm, loved, well fed and spoiled. I had to end his suffering due to the fluid causing him to have respiratory distress. He was only 3yrs old.RIP HEMI. I miss you so much buddy😢🐾🌈❤ 3-12-21
My cat got FIP about a month and a half ago, and I can tell you that he is recovering amazingly. There is an official legal study being done by a group of vets in Ontario Canada. It uses two separate drugs both in pill form and both from legitimate sources here in Ontario. Not black market sources. The vets got authorization from the manufacturer for the gs drug for the study. They have around 240 cats in the study so far and a 90-95 success rate. You’d never notice that my cat was sick to look at him now. Once on the medication improvement is within 48-72 hours.
Wow sounds really promising! FIP is arguably one of the most frustrating diseases in cats to deal with due to its high infection and mortality rate, so it’s great to hear that there is finally a potential drug on the market that could be curative! Would love to track its progress, could you perhaps provide the link to the study that had been performed Dr Alex?
my bengal kitten boy is 8 months old and has seemed to develop this disease, it’s truly heartbreaking. i’ve only had him for around 4 months and in that short amount of time he has become my other half. he lost so much weight, has become anemic, not eating, really lethargic, not himself at all, pale gums, finding trouble walking… he’s currently at the vet undergoing treatment and having tests done, if FIP is detected, or should i say signs as they can’t get a full on diagnosis he will be getting treatment that costs around 2-3k i’m so fortunate i’m able to afford it, i just hope he makes it through 🙁 he seems to be deteriorating right infront of my eyes 🙁 really wish this treatment becomes more affordable so other owners don’t have to go through the horrors of having to let their beloved pet go due to this cruel disease 🙁
i’m writing this hoping there is a light at the end of my tunnel, as well as the individuals fighting to keep their kitty alive. about two weeks ago, i took my kitten (blue eyed white fluffy persian/himalayan) kitten to the vet for his first round of vaccines. all the sudden, a couple days later he has a pot belly. last night i finally took him to the vet, where they drained enough fluid to treat at the lab for the disgusting fip virus. the liquid she said did not travel to his chest, but was a light yellow color. my baby is just 2 1/2 months old. i’m so attached to him, he’s beautiful. until the test comes back monday from the pet hospital, the vet i took him to for his first round opens sunday. i’m just thinking to myself, how is it fip if i purchased him healthy and two weeks ago the vet said he’s a healthy kitty? they checked everything at that appointment? i’m so struck by this and i’m praying, god please this too shall pass. i’m praying that this is something curable, that this test comes back negative. i pray over everyone and their kitties with the same symptoms, and that mine along with their furry babies live a long and healthy happen life🙏🏼
Im trying GS for two strays (not random strays, but the ones i feed everyday) right now. One has neurological FIP (hind legs imbalance+lameness), one has wet fip (pleural effusion). We’ve only injected it for 1 week… The one with neurological improved dramatically, gain 150 grams, eat normal, walk better. The one with wet fip still hasnt showed much result but not deteriorating either. I didnt put my hopes high but now that i do see difference, fingers crossed Update: As per 23rd may 2021, two weeks before the treatment supposed to end. The one with neurological FIP has gained 1.5 kilograms o_O activity and appetite totally normal. The last blood result, albumin normal, globulin only slightly high (His a/g ratio used to be 0.2 and now it’s 0.5) The one with wet fip, we discontinued the treatment bec apparently she has CKD, but until now the pleural effusion hasnt reappeared We treated the 3rd cat with FIP (wet, abdominal) and it’s our 2nd months. The effusion has disappeared completely, his activity and appetite is 100% return to how it was before
I just lost my Travieso, my 10 month old kitten this morning to FIP, and his brother Gordo 3 months ago. I rescue, foster and I’m a volunteer trapper for my local city’s TNR Group. I was never made aware of the possibility of exposing this deadly disease to my own cats until my Gordo passed and I was told he had FIP!!! Now I’m very concerned for my other cats and I really don’t know what to do to mitigate this issue I brought home to my fur babies!?!? My Vet informed me that all of my cats have been exposed and that I should keep an eye out for any of the symptoms mentioned in this article. I would greatly appreciate any advice and or suggestions on what to do now that exposure has happened🐾🙏🐾
My 1 yr.old kitten cat . She was an Egyptian forest cat I had to put her down. She had FIP. The first symptom and only one was occasional bouts of diarrhea. She ate well. Played hard and seemed very healthy. This started at around 5 months of age. Then her belly was getting big. She ate well. I believed she was getting in the sink and drinking water with soap in them or the hubby ice cream. I was very wrong. Two weeks ago she started throwing up. 5 days before I took her to the vet she started mouth breathing and her nose was plugged up. She just turned 1. She was a great cat. I have 2 other indoor cats as well. They are 6 yrs of age. One is siamese and the other is mixed . Both have shared a litter box with her. My siamese was grooming her till the end . She is out of pain now. perusal her suffer was horrible! I’m having sleepless nights. She slept with me. But I am worried about my boys. Thank you for sharing this article.
I just lost one of my foster kittens to wet FIP. He had the classic abdominal fluid bloating. Sadly, he was rescued from a stray cat colony where he was likely exposed to feline coronavirus. I’m in the facebook group FIP Warriors where members are sharing their success using GS to treat their cats. For my foster kitten, it was too late as he was going into organ failure, so we opted to let him go. I hope that one day we will have a widely available treatment for this.
This is the worst disease I’ve ever known. I lost a cat to it 4yrs ago and it was the worst thing I’ve ever lived through. It is still relatively poorly understood and unfortunately this new treatment is completely unaffordable for most owners. My heart goes out to you if you are going through this with your cat, I thought I’d never smile again or have another cat. I now have 3 healthy thriving cats…the eldest one, with me throughout the trauma, remained unaffected by corona or fip. I was told by a vet that I couldn’t have anymore or this would come to them…..Utter nonsense! I got 2 more cats and all 3 are thriving. Fip is extremely random, I spent 2yrs after losing my cat researching this disease. I read every paper available and communicated with Mr Pedersen the fip expert. Imo, all the cleansing, disinfecting and precautions in the world will not stop it happening. My cat was a Birman and they are known to succumb to it therefore I will never own a Birman again and I would advise against that breed if fip is a concern to you. I still to this day carry pain and grief over it, it will never leave me. But know this, there is life after fip and you will go on to experience the joys that your next cat brings you. It is a disgrace and a shame on pharma and government that this treatment is not made more affordable.
My cat developed massive ascites at about 10-12 years of age. He acted well otherwise except for the abdominal discomfort. His bloodwork had normal kidney and liver functions. His white count was elevated. My vet tapped his abdomen and removed 1.5 liters of fluid. However, no I. V. Fluid replacement was offered. He deteriorated rapidly after the tap and died the next day. I think he died from probable cardiovascular collapse from the excessive fluid removal. Studies ordered on the ascites fluid were cancelled by the vet without my knowledge when he died. I really wished to know the cause of his ascites. I also think he could have been given better supportive care. I would appreciate comments on his case (I am a retired pediatrician, very familiar with health care options).
Hello Sir. I’d like to ask you a question. I have a 2 y-o cat. I adopted her 15 months ago. She was a stray cat here in Istanbul Turkey and tested FCOV positive on Elisa test kit almost a year ago. I had her tested with other various tests as well including RT-PCR, full blood count and biochemistry lab tests. She’s FIPV negative according to the repeated RT-PCR tests. Thank God, her ALB and GLOB levels are also in normal range. Should I still worry about her and my other cats as well? They have no symptoms whatsoever but I’m all the time down with “what if…” questions. They have all been tested FIPV negative in RT-PCR tests. Looking foward to hearing your response. Thanks in advance. Bests.
Is raspy breathing, but otherwise healthy in every other aspect (as it appears to be in my unexperted opinion, eating, drinking, purring and active) something I should be concerned about? Shes been a heavy breather since I got her 3 years ago, she was vet checked by the rescue centre I bought her from..Is this virus something that can be over looked or undetected easily?
My 2 years old cat diagnosed FIP this january, he diagnised have a fatty kidney at first… He lost ability to walk gradually since Jully. Now he just layingdown on side of his body (can’t roll over), so we have to feed him by injecting food and water to his mouth, some time he can take a small bites of boiled chicken… I’m glad he could survive this long, but it really broke my heart to see him like this.. idk what to do since the vet said there is no cure, and no medication to ‘fix’ his motorics
Hello buddy ✌️ Dr Alex I see you have a hoodie with our pets health logo on it I’m going to order it and show everyone and tell them about your website I think of you in the highest way my friend 👍, I used to have a cat named boots. I named him from boots Randolph the saxaphone player.lol..i miss ol boots he was 17 when he left on March 3,1995..I never did find him he was a grey tomcat with white feet and his hind legs were white half way up and it’s how I thought of boots…I went to my vet day before yesterday and I was talking to a worker there I had to go get bigfoot meds and I was talking to her and she said my Dr said I was one of her best clients because I care about my animals she said alot of people bring a pet to the doctor and get meds and then never come back to have it refilled and then they sometimes bring back the pet and usually it’s too late to help it .I asked if they had a lot of senior dogs come there and she said oh no it was me and one other person who has senior dogs they other being a beagle 17 years old and I know the lady who has him his name is Charlie the beagle… well thank God so far Bigfoot is doing pretty good and Arnold is too… thanks for the article ✌️ buddy 👋😊 good to see you again my friend take care of yourself buddy 👍🙏
Can it end up in one lung mimicking congestive heart frailer?She was 14 one min she was running around the next she stopped eating! her White count was high and I was sent home with zeniquin the 2nd vet took 110CC out of her chest? she suffered because they couldn’t figure out what was wrong plus she was exposited to human covid she wasn’t overweight and was extremely active running up a cat tree to the ceiling and jumping up to a bookcase I have a hard time believing heart failure happened in one night
Hello i am a new cat owner and my cat is currently diagnosed with FIP and receiving Gs44 injections, currently we are in our second round of 7day consecutive injections, however my cat developed a bump over his neck where he receives the injections, i have raised this with the vet and she took a syringe to aspirate, and one sac was airfilled the other with fluid blood tinge, is this a side effect of the injection? Or this is a cause for alarm, as of this writing i rechecked my cat and i can sense another bump over his injection site
Please please… let your viewers know that the treatment is available even tho is not yet approved. Cat owners have the right to try save their cats. I was advice to put my cat to sleep yesterday and later on I found out that people are using this treatment already with very goods results. I wish this information was given to me before since it is not right to say that there is no treatment bc there is. Im heartbroken because I know my cat would have survive this. She was much still having appetite, jumping her tower and going bathroom on her own. She was a fighter and deserved a chance besides putting her to rest 🙁 cats in worse conditions than her got better in the first days of treatment. So please inform people there is a choice even if doctors cant officially administer them. I would have done everything to have her back and hate the fact i found this only after her death. Please!
We’ve been treating our kitten for wet FIP with GS. He has had 6 weeks worth of injections, he is doing fantastically. We are thinking about stopping his treatment as he is doing really well, and not completing the 12 weeks, do you think think that this is the right decision? His blood test at 4 weeks into treatment showed his alumni/globulin ratio was fine. I’m so unsure as what to do.
Hello, how long is the life span of a cat that has been diagnosed with FIP (wet)? My cat was diagnosed to be FIP+ and the veterinarian told me that the cat will only live for about 3-4 months. Now it’s been 7 months since the diagnosis. How can I be so sure if the diagnosis was wrong? My cat is very well. P.s. the vet used rivalta test. Thanks.
My cat have fluid buildup like crazy. The vet thought it was caused by a heart disease but they couldn’t see anything on the xray neither with the ultrasound due to all the build up of fluid. Instead they tried to drain him of fluid. I got to see the fluid in the tubes they extracted and it was quite yellow but also transparent almost like urine. Could that be FIP? They didn’t mention anything about FIP. He is 15 years old and have had problem with watery eyes all his life. It looks almost like blood cloths around his eyes. They say it’s a 50/50 chance of him surviving if we start giving him the blood pressure medication. But they haven’t even been able to listen to his heart due to all the fluid and also they haven’t done a blood pressure test either. Tomorrow we’ll go back with him to the vet and let them drain more fluid. I read online about GS-441524 . Is it worth a try when they don’t know whats causuing the fluid build up or is it to late to do anything if the wet form already gone this far?! He has trouble breathing due to buildup around his lounges. Not that he is panting but you can see him breating all down in his belly.
I fostered a litter of 4 newborn kittens and all of them had huge bellies. One by one they started to fade, and I held them as they died. 😢 I have one kitten left, and she’s 4 weeks old. Her belly is still totally bloated, but the vet doesn’t seem a bit worried. He isn’t interested in doing a fecal exam or any blood work. Maybe it’s because she’s a feral street cat. I am so angry and frustrated. I’ve been bottle feeding her every 2 hours around the clock, and I’ve become very attatched to her.
My kitten (5 mos) has been having bloody stools, sometimes soft, for about 3 mos now. He was diagnosed with giardia now but we are pretty sure he has colitis now. The doctor has him on antibiotics rn. He has red veins on the white parts of his eyes so the doctor is keeping his eye on him for FIP just in case. Is bloody stools a sign of FIP?
I have a 11 months bengal boy. Recently he started sleeping a lot and had diarrhoea and had fever. We took him to the vets, they done test and kept him over for few days. They told us everything points at FiP. They diagnosed him with anemia. His blood cells did rise so fingers crossed. Atm he is on steroids, eating and drinking well, using cat litter as he should, trying to play but gets tired quicker.he also loves sitting on his big cat tree. We want to give him a chance of survival as we think he does not have this disease but he might have something wrong with his stomach? Any ideas?
I wonder if this is what my cat had, he was older though, had fluid on his lungs, they had mis-information on his thyroid & used money as a barrier to treatment. Absolutely awful emergency care he had. I’m so proud we now have a local emergency vet who I know are good, it’ll make it easier if we need emergency treatment which I think we came close to needing once (we had to check when their emergency hours kicked in, 10pm weekdays and 12pm Saturday until opening on Monday) they’re up by our local Asda which is good, most clinics have been out of the way, they build a new place and moved and they don’t realise just how central and important that is to the housing estates they’re nearby.
I put my cat down last week a 7 years old beautifull loving and amazing healthy cat, he started to caugh 2 years prior and lost apetite i saw his abdomen contracted as he was breathing i though of asthma, i brought him to the emergency clinic, i was never told about fip but he had water on the lungs they said no chance most put down i did broke my hearth and found out about fip 2 days later, why dont vet know about this my hearth is so broken,i wish i knew 2 days earlyer my baby would still be with us, so sad i am so angry 😢
We have a 9 month cat and he just keeps getting fatter. Our other cat though is super skinny. I can’t tell if it’s obesity or a underlining issue. He does kind of breath heavier but seems to be ok. He plays, runs, eats a lot. He does meow when going the bathroom. I’m so confused at what exactly might be the issue with him.
My cat is diagnosed with wet FIP he is 6 months old. 2 days ago he started sleeping a lot and lost energy and any will to play. So i took him to the vet yesterday they said it is most likely FIP. This morning the belly got big and I just took him from all day of tests and they confirmed its FIP. They told me £8000 for the treatment and there is no guarantee. They told me 1-2 weeks remaining. I don’t have this money and its not covered by the insurance, so i am wondering is there anyway getting the drug myself in the UK as i couldn’t find. I found one place they sell 25mg for £587. Is that enough what kind of dosage? Please help ASAP
Does anybody know about the survival status of those 24 cats? Also, my cat is diagnosed with the wet form of FIP. We just started to the first dose of GS. He is over 1 year old and his belly is veryfluid, I hope he will be fine. I wonder if he gets well soon after 84 days, is it possible that he will get back to FIP?🙏
I have five cats all four have the herpes virus. But it’s dormant it’s in recession I have one cat that is sneezing and wheezing and doesn’t seem to want to eat anything. I noticed symptoms today. Sadly I do not have money for a vet bill. And she’s my main cat. I had to treat two cats for herpes and put it in remission and that cost me 600 bucks. But this cat is only sneezing and wheezing with clear liquid coming out of its nose and watery eyes.
My wife and I just lost our 16 year old cat that I think may have had dry FIP. I know normally FIP hits young cats but it can affect older cats as well. Vets were telling me that she had Small Cell GI Tract Lymphoma, but we couldn’t know for sure since she was already weak. Her blood work gave impression of infection, she had watery eyes as if she was crying with gunk around it. She suddenly developed a slight heart murmur and was having difficulty keeping her balance which I had taken as well as thickening of the intestinal wall with issues with crystallization in her Kidneys. The last report I saw was the day prior having to euthanize her was an xray which did not show any tumors or masses but there was free fluid/air in her abdomen. The issue I have with the original diagnosis was that Small Cell GI tract Lymphoma normally takes a while to kill a cat but the process from initial symptoms to her dying was 1 month. We had her on pred and clorumbucil which seemed to help her feel better but made no difference in the long run. She went from 6.5 pounds to 4 pounds in 1 month. I know it makes no difference now as she’s gone, I guess I just want to know the why of it all, and if we had been looking for this would we have been able to get the meds to her in time. I’m very glad that your story had a happy ending, and I wish more awareness is put on this disease so folks don’t have to learn about it after you say goodbye to your furr baby.
Hi May, my cat also had Parvo and dry FIP when he was 7 months old, but thankfully he recovered! This is definitely an emotional but very meaningful journey, a reminder to appreciate our lovely companions more. Thank you for the very informative article, I can feel the love you have for Keith! He’s very lucky to have you – and vice versa 😉
Thank you for sharing Keith’s story May! The both of you have been an inspiration to not give up even when the going gets tough. I aspire to be an awesome vet like you as I approach the end of my veterinary degree. Thank you for shedding your experiences and I hope that Keith continues to live a long and happy life!
As a neonatal kitten rescue, we run into fip quite a bit, GS is a lifesaver and you nailed all of the big points! In the US it is still a gray market drug, So can’t be prescribed, but I can hold it in my hand and administer it as somebody who is not a vet. We have two cases currently that are doing well!
I have 20 cats and it all started in my youngest after she was spayed! I ended up with four cases. The GS wasn’t legal here either and I was running everywhere to get it. To cut a long story short 2 cats made it but 2 died as treatment started too late! The 2 that made it are touch wood doing well now 8 months on. I stayed with the GS injections for 6 weeks as my vet recommends a minimum of 4 and then changed to molnupavir (esperavir) for the last 6 weeks. The whole outbreak cost me several thousand euros! But at least I saved 2!
13 minutes in, somebody’s cutting onions. About 2.5 weeks ago, we rescued 3 week-old foster kittens that had been abandoned by their mother and left in the attic for about a week. We immediately took the weakest one of the three to the vet, but unfortunately, she passed away just a few days after we started caring for her. Now there are two kittens left, and one of them has suddenly become lethargic, lost its appetite, and has bad diarrhea. Just an hour ago, I saw blood in his stool. I’ve never felt this helpless about a pet before. I helped them poop and pee for our first weeks together, and now that they’re getting bigger and can do it on their own, they’ve gotten sick. I was planning to take them for vaccinations and deworming when they turned 6 weeks old, but I’m afraid they already caught something now. I feel like a bad kitten parent. Just before these little ones, I had to hospitalize a stray kitten that hung around our yard, but it passed away 1.5 weeks ago. A year ago, I took care of 3 stray kittens, but they all got sick and died. And the year before that, I cared for 4 stray kittens who also passed away after multiple vet visits. My heart can’t take it anymore. I’ve been babying these two, and they’re still sick. I’m so afraid they will pass away too. I feel so weak typing this.
Found this vid when looking for articles on how to deal with a VERY angry cat in pain while injecting. Mine is bloated, no muscles and I can feel his bones, including the spine. Blood test was done, vet says fip. Germany hasn’t legalized the drug. So Facebook it is. Everything is Super shady, after they hooked me up with my first 7ml for 90€ vial they ignore me. Your cat is super chill when injecting. Mine goes nuts. Will switch to pills in a few days.
Thank you for sharing. I’ll be happy when Remdesivir is legal in the US. We lost a couple kittens to FIP before this drug existed, and another one this spring – we’d have treated him but he was misdiagnosed and we only learned he had FIP as a result of the necropsy. We had suspected and ordered a course of treatment but he was already so sick he died before they even arrived.
I feel you. My FIP cats died after blood transfusion last year. I work as Veterinary Assistant yet I didnt notice his condition😭 And this year my other cats got infected with FIV since he is semi indoor cats. He start his treatment right away on 2 January. He also has mycoplasma, his kidney was infected, anemia and need to do blood transfusion. I feel bad that I couldnt pay enough attention to him since I have 18 other cats at home…
I’m in Brazil and can tell you that the situation — as far as availability and ‘legalities’ go — still has not changed for most of the world, unfortunately also, from all the things that I read, the pandemic only complicated matters insofar as the cure’s availability for cats goes or to be more specific; the pharmaceutical company that owns the patent hasn’t made it available for veterinary use only because attempting to do so (in the midst of the urgency caused by the pandemic) would require additional clinical trials which could generate data which could adversely affect its approval for use in humans — or so the story goes anyway, glad to hear that it’s easier in the UK, at least; ..and, of course, that Keith won his battle against FIP
Hi May I’m happy for Keith is healthy and happy after this terrible disease. My cat was also diagnosed FIP and we are doing GS-44 injections and they are working well but they are very painful. Do you remember how many injections Keith got before switching to pills? What indicator in him did you use to know that’s the time to use pills instead? Thank you so much for sharing your story
Our kitty ( 7m/o female) is suspected of dry fip. neu 70% lym 17%. with high glob and .6 a/g. elevated protein and white blood cells seems to be in pain, hides and pees on floor. less of an appetite. started gs treatment today, hoping threres improvement. I find that prednisolone helps them have a better appetite.
I’m a 34 year old program manager working in a big tech company in Silicon Valley. I’ve been contemplating to get a career change to become a vet. But I’m not sure if it’s too late now, because to become a vet in the US I need to be school for another 6 years, by then I’m already 40 years old. Now I’m considering becoming a vet tech, that one is 2-4 years of school
I just found out today my newly adopted rescue kitten (barely a week with me) has FCOV. The vet made me confine her and advised that even if she survives this, i have to separate the kitten and my FCOV negative resident cat. I was wondering if you have any advice, especially on the topic of separation.
I have a British blue that has just been diagnosed with the most severe form of FIP. She is currently having daily remdisivir injections on day 4 now. Has 2 more injections then on to 11 weeks of daily tablets. It’s been very hard for her and traumatic as the injections are painful. I’m dreading doing the daily tablets as she is so aggressive at the moment, and we have only had her for 8 weeks and has been unwell for 7 of those. Fingers crossed she gets through this and am determined to get the medication down her. Towel wrap is the only way I think.
Thank you for the great article!! My cat passed away a few weeks ago with suspected FIP. Now my other cat is suspected to have FIP too, she is eating and no problem but she started to have eplipsey a few months ago randomly. I tried to get FIP treatment, and did go to FIP warriors but they directed me to a EU link to buy those drugs I have not heard of… any suggestions please?
My boy Axel has been diagnosed with pleural effusion, most likely as a result of FIP. My vet didn’t want to stress him more by trying to do a blood test and basically suggested euthanasia. He is only 1 year old, that seems completely unfair for him, so I have set off on the quest of trying to help him live. I believe Remdesvir is thousands of dollars here in the US. Does anyone know of a way to get it at a more reasonable price, or some kind of fund raiser that could help in just a few days I might have to make a decision? Thank You.
my nine month old kitten got diagnoised with FIP around a month ago, we didnt know what was wrong with him and we took him to multiple hospitals one finally said that it might be FIP so we tried everything, didnt work then he started having sezuires and we thought he wasnt gonna make it, but thankfully my parents did lots of research and found a group of people who helps us find FIP medicine near us, so that night, my parents drove two hours to san diego to give him a shot, now he has to take a shot everyday for around 80 days