Cymbalta, also known as duloxetine, is a prescription drug used for treating major depressive disorder. It is a SNRI antidepressant that can cause side effects such as diarrhea, nausea, and constipation. These side effects usually improve over time as the body adjusts to the medication. Some users report severe diarrhea as a common side effect of Cymbalta, which may persist for weeks or months and affect the patient’s overall health.
Duloxetine is a prescription drug used to treat various conditions, including depression, anxiety, and pain. Common side effects include blistering, peeling, or loosening of the skin, chills, cough, diarrhea, itching, joint or muscle pain, red irritated eyes, red skin lesions, and sleep problems. These side effects may be temporary and may resolve within a few days or weeks.
Some common side effects of Cymbalta include dizziness, confusion, mood swings, headache, tiredness, diarrhea, sleep changes, and brief feelings similar to those experienced with other antidepressants. If these side effects become more severe or do not go away, it is important to consult a doctor or pharmacist.
In summary, Cymbalta is a prescription drug used to treat depression, anxiety, and pain. It can cause side effects such as diarrhea, nausea, and constipation, which may persist for weeks or months. It is crucial to consult a doctor or pharmacist if these symptoms persist or worsen.
Article | Description | Site |
---|---|---|
Duloxetine Side Effects: Common, Severe, Long Term | It is possible that these side effects will dissipate during the course of treatment as the body becomes accustomed to the medication. Additionally, your healthcare professional may be able to discern… | www.drugs.com |
Cymbalta side effects: What you should know | Cymbalta has been associated with a range of potential adverse effects, with some occurring with greater frequency than others. Such adverse effects may be transient, with a duration of several days to a few weeks. | www.medicalnewstoday.com |
1590 Another Case of Duloxetine-Induced Lymphocytic … | The patient presented with diarrhea of unknown etiology for a period of one month. The patient indicated that the diarrhea commenced six weeks after initiating duloxetine therapy. The patient reported approximately five episodes of explosive diarrhea. | journals.lww.com |
📹 3 Things You Should Know Before Taking Duloxetine (Cymbalta)
In this episode, I discuss three things that you should be aware of before taking duloxetine (Cymbalta). My book is now available!
Why do antidepressants cause diarrhea?
Effects on the GI tract are mediated stimulation of serotonin 3 and 4 receptors. This stimulation can lead to increased GI motility, GI cramps. If the increase in GI motility is severe enough this can lead to diarrhea.
What is the hardest antidepressant to come off of?
Selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs) are the most likely antidepressants to cause withdrawal symptoms. Listed according to their risk of causing withdrawal, they include:
- Desvenlafaxine (Khedezla, Pristiq)
- Fluvoxamine (Luvox)
- Paroxetine (Paxil, Pexeva)
- Venlafaxine (Effexor)
- Citalopram (Celexa)
- Duloxetine (Cymbalta, Drizalma)
- Escitalopram (Lexapro)
- Sertraline (Zoloft)
- Fluoxetine (Prozac)
- Levomilnacipran (Fetzima)
- Milnacipran (Savella)
How long does it take for the side effects of Cymbalta to go away?
When starting Cymbalta treatment, some people experience mild side effects such as nausea, drowsiness, dry mouth, or constipation. Most often, these duloxetine side effects and symptoms go away within the first week of taking the drug. However, you should contact your doctor if any symptom persists or worsens over time.
During week two, Cymbalta may alter brain chemistry, which could result in heightened depression or suicidal ideation. If such feelings arise, consulting with a physician about adjusting the dosage or switching medications is essential. If you start experiencing any new feelings of hopelessness or despair, talk with your doctor right away about reducing your dose or switching medications altogether if necessary.
- Exhaustion
- Headaches
- Difficulty sleeping
- Constipation
- Diarrhea
- Increased urination
- Blurred vision
- Nausea, vomiting
- Increased sweating
- Dry mouth
- Change in weight
- Reduced appetite
- Sexual dysfunction
Serious Side Effects of Cymbalta. Cymbalta can be an effective treatment for depression, anxiety, and pain, but it’s important to weigh the associated risks before taking it or any other antidepressant.
Can Cymbalta cause diarrhea?
Mild side effects that have been reported with Cymbalta include:
- Abdominal pain (stomach pain)
- diarrhea
- dizziness
- dry mouth
- drowsiness or fatigue
- excessive sweating
- insomnia
- heart palpitations
- loss of appetite
- nausea *
- headache *
- sexual side effects*
- constipation *
- mild allergic reaction *
These side effects may be temporary, lasting a few days to weeks. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.
Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. If you develop a side effect while taking Cymbalta and want to tell the FDA about it, visit MedWatch.
How can I reduce the side effects of Cymbalta?
How to avoid Cymbalta side effectsTake Cymbalta as directed. … Read the medication guide. … Tell the doctor about all medical conditions. … Tell the doctor about all medications being taken. … Do not stop taking Cymbalta. … Do not drink alcohol. … Be careful about driving and other risky activities. … Avoid NSAIDs.
Most Cymbalta side effects are temporary, lasting only a day or two, but some side effects can last for weeks.
Cymbalta (duloxetine) is used for treating depression, anxiety, and pain related to fibromyalgia or diabetic neuropathy.
Common side effects of Cymbalta include nausea, headache, and dry mouth, and are often temporary. Serious side effects like serotonin syndrome, angle-closure glaucoma, and liver failure may require hospitalization and longer recovery times.
Do Cymbalta side effects subside?
Common Side Effects Common side effects such as nausea, headache, muscle pain and dry mouth may dissipate a couple of weeks after starting treatment.
The most serious side effects caused by the antidepressant medication Cymbalta (duloxetine) include abdominal bleeding and liver injury. But stopping the drug suddenly may cause withdrawal symptoms such as anxiety, agitation and suicidal thoughts.
The most common side effects of Cymbalta are nausea, headache, dry mouth and sleepiness, but more serious side effects may occur. A 2021 review of Cymbalta clinical trials found that participants who took the drug were more likely to experience common side effects than those who took a placebo. But people who take Cymbalta and don’t participate in drug trials also routinely report these side effects.
Selective serotonin and norepinephrine reuptake inhibitors (SNRIs) such as Cymbalta and selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants for major depression. Unfortunately, almost all can cause these side effects, leading many people to want to stop taking them.
How to heal your gut after antidepressants?
Results According to the study’s inclusion criteria, twelve studies out of 300 articles were selected for the qualitative analysis. In the in-vivo studies, animals administrated with SSRIs had a decreased abundance of Firmicutes, Alphaproteobacteria, Bacteroides, Ruminococcus, Adlercreutzia, Turicibacter, and alpha diversity but an increase in Prevotella, Parabacteroides, Butyricimonas, and Alistipes. Besides, antidepressants were shown to exhibit significant in vitro antimicrobial activity against Akkermansia muciniphila, Bifidobacterium animalis, and Bacteroides fragilis, suggesting that the chronic use of antidepressants potentially causes adverse effects due to their antimicrobial effects and dysbiosis ( IDDF2021-ABS-0164 Figure 1. Illustration of gut microbiota dysbiosis in response to antidepressants). Probiotics, prebiotics and fecal microbiota transplantation are shown to be promising strategies to ameliorate antidepressant-associated dysbiosis.
Conclusions Understanding the interaction between antidepressants and gut microbiota, including dysbiosis as a consequence of treatment and potential side effects, is vital for the future development of better and personalized treatment. Supplementing the gut microbiome with prebiotics/probiotics could be an adjuvant treatment to improve the clinical efficacy of the current antidepressant therapies.
Request Permissions. If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
How do I stop diarrhea from antidepressants?
Diarrhea is a common side effect of antidepressant treatment, which can be transient or persist in some patients. A meta-analysis of 84 trials found that 16 out of patients taking SSRIs experienced diarrhea, with 78 experiencing it at 2 weeks and 45 at 3 months. Management of diarrhea can include antidiarrheal agents like loperamide, diphenoxylate hydrochloride, cyclproheptadine, Lactobacillus acidophilus culture, and psyllium.
Constipation may emerge during antidepressant therapy, with paroxetine being associated with the highest rates due to its high affinity for muscarinic receptors. The rate of constipation is 11 to 12. 5, with 4. 7 of patients describing it as a bothersome side effect. Bulk-forming laxatives, stool softeners, osmotic agents, bcthancchol, and cholinesterase inhibitors may be used when pharmacological management is required.
Weight gain is another bothersome effect of antidepressant treatment that may interfere with treatment adherence and general health. It is often difficult to study because it can be a sign of improvement in patients with weight loss as a symptom of depression, a residual symptom in patients who overeat when depressed, or something independent of depression or its treatment. Many long-term studies show no difference between SSRIs and placebo, except for paroxetine showing a significant difference from placebo. In a study comparing the rate of weight gain on antidepressants, mirtazapine was associated with the highest percentage of patients with weight gain, followed by SSRIs and venlafaxine. Nefazodone, bupropion, and rcboxetine result in the lowest rates of weight gain during treatment.
Will Cymbalta sweating continue or go away?
Other side effects are more likely to continue for as long as you’re taking the drug. Examples include sweating more than usual and sexual side effects. These side effects usually aren’t severe.
Cymbalta side effects can affect each person differently. For example, nausea may be a mild, temporary side effect for some people. For others it can be bothersome. In studies, a small percentage of people had to stop taking the drug due to nausea.
If you’re experiencing troublesome side effects, you shouldn’t suddenly stop taking Cymbalta. It’s best to talk with your doctor first. If you and your doctor decide that you should stop the drug, they’ll guide you on how best to do so.
Do seniors have a higher risk for side effects from Cymbalta?
What is a bad reaction to duloxetine?
This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome /toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/ diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching /swelling (especially of the face/ tongue /throat), severe dizziness, trouble breathing, skin blisters, mouth sores.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at fda. gov/medwatch.
Does Cymbalta constipation go away?
How long does Cymbalta constipation last?. Sometimes, side effects are temporary and subside as your body adjusts to the medication. Cymbalta constipation should resolve within a few days to a few weeks as your body adjusts to Cymbalta, according to Amy Lee, MD, chief medical officer of Lindora Clinic in California.
“The time frame is different for everyone,” Dr. Lee says. “But you can definitely prevent it by doing all you can to keep your stools soft!”
Management and treatment of Cymbalta-induced constipation. “Knowing that this medication could cause constipation, make sure you drink plenty of fluids when you are on the medication,” says Dr. Lee.
📹 5 Things You Should Be Told When Starting Medication for Anxiety and/or Depression | SSRI/SNRI
5 Things You Should Be Told When Starting Medication for Anxiety and/or Depression | SSRI/SNRI. When being prescribed …
Opposite for me. It worked for 2011 to just recently 2024 july. I’ve upped my dose but I’m still crying. Even worse, I’m 62 years old and lift weights to help my depression. I’m pretty strong, deadlifting over 400lbs. I didn’t realize how well deloxitine relieved my muscle and joint pain. 😢 Now my depression is back and cry over a sad movie and i have unbearable pain. I’m starting to use ibuprofen which i dislike because of potential harm. Use it if it works. It’s been great for me. Life is harder with out it, if you know what i mean. Pain and sadness is a hard way to live. God bless and i hope this helps someone. ✌️🙏☺️ Ps remember, your body and brain will take a few weeks to get used to it. So give it a chance. Definitely worth it if it works for you. I did run out and didn’t prepare, so I did go thru the side effects of quick stoppage of meds. But if you know it’s coming, it’s easy to deal with. Just don’t be like me and order your refill before you run out. Good luck.✌️
On it: extreme introvert, hyper fixated on certain stuff, will put everything off that doesn’t interest me or find excuses not to do it, dreads leaving the house for any reason & can’t tolerate being in social settings for long periods of time without losing my cool. Over all not depressed, and my mind is quiet for once my ADHD is actually tolerable my head space feels peaceful. Miss dosage or if I take it later than I should: Violent mood swings, thoughts of wanting to murder someone (usually a certain individual who wronged me and caused me to have a mental break down and have to be on this shit meds in the first fucking place I won’t say the person name) obsessive & intrusive thoughts. Extreme negative downward spiral of negative suicidal thoughts, agitation, easily annoyed over anything and everything. (this is coming from a person who doesn’t have anger issues just depression and anxiety) this med makes me fucking crazy and I hate it….. But if I manage to take it on time my mind is quiet which is something I’m not use to my ADHD has always made me overthink 24/7 so it’s weird not having my mind constantly thinking about stuff.
The most important thing to know about duloxetine before taking it is that you could have extremely bad brain zaps for months after tapering off. It is absolutely not worth it, if you’ve never experienced these before there just is no way to describe how miserable they make you and how badly they affect your life and yet since they aren’t common knowledge you likely won’t get sympathy from your employer about it
My husband was on this almost a year for elbow pain from injury. He felt ok for a week then got insanely anhedonic. They bumped his dose up saying he was depressed from the pain, he was a zombie. He tried tapering with miserable side effects, a week ago he just stopped and as of tonight is in full blown delusional and aggressive psychosis and rhinks ges fine!. Look up the patient experiences, suits against Eli Lily etc. These drs should be ashamed of pushing this drug knowing the company has been ruining lives for over a decade. It acts similar to tramadol and it does affect opiate receptors while suppressing dopamine. There is no good in this drug or the “professionals” that push them.
Also, duloxotine is highly physically addictive. Withdrawing will cause, irritability, loss of coordination, brain zaps, concentration issues, adrenaline spikes and dumps. It’s not a good one to get off. Having said that, if I’m on it, I’m good. The problem is I want to know what I’m like off it after 15 years but can’t
I recently came off of Lexapro about 2 months after 4 years of taking it until it stopped working. My doctor wants me to start taking cymbalta, and I’m uncertain about taking it. Mostly the fear of the side effects. I tried celexa after the Lexapro, and all it did was gave me insomnia (not staying asleep) bad dreams, and sense of losing control of my thoughts and feelings
This stuff has been amazing for me. It took 2-3 months for it to stabilize me. I titrated myself to 40 mg. Separating the little beads in the pill. For a month. I was scared to take this stuff because of the stigma, and ignorant comments. Anyway, I then went from 40mg to 60mg. It’s been about 2 years. I’ve discussed titrating off with my drs. I love being on this stuff tho. I feel normal. ❤ I wouldn’t mind taking this for life! I hope this has trained my brain chemicals, so when I eventually do go off, I hope my brain will pump out enough, to what level I was at while ON the medication. I hope this helps someone!
Im 14 months into 30mg duloxetine daily. It has been Very good in my experience. I had backpain that really limited me. It has definitely helped with that. ( lower disk pain). Ive had depression for 30 yrs. Ive had problems letting go of women, not good for me. For some reason, i just seem to not react like i used to. Im talkin bout the reaction in my moods, and attitude. I can deal with those things better. Im not freaking out on the inside, as i once did. Ive had issues with premature ejaculations all my life. Now tho, i last and last. Sometimes, i dont cum, unless the chick is really into our moment together. Not taking duloxetine, does make me feel shitty. But so does, not having morning coffee.